Gene: GRK4 ENSG00000125388

Description

G protein-coupled receptor kinase 4 [Source:HGNC Symbol;Acc:4543]

Gene Synonyms

GPRK2L, GPRK4, GRK4a, IT11

Location

Chromosome 4: 2,965,335-3,042,474 forward strand.

GRCh37:CM000666.1

About this gene

This gene has 11 transcripts (splice variants) and 15 paralogues.

Transcripts

Show transcript tableHide transcript table

Transcript ID	Name	bp	Protein	Biotype	CCDS	UniProt Match	RefSeq	Flags
ENST00000398052.4	GRK4-001	2202	578aa	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS33946	P32298	NM_182982.2	A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000503518.2	GRK4-004	2136	84aa	Gene/transcipt that contains an open reading frame (ORF).Protein coding		D6REW5	-	A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000398051.4	GRK4-002	2068	500aa	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS68656	P32298	NM_005307.2	A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000345167.6	GRK4-005	2013	546aa	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS47002	P32298	NM_001004056.1	A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000504933.1	GRK4-012	1971	532aa	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS33947	P32298	NM_001004057.1	A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000442472.2	GRK4-201	1018	134aa	Gene/transcipt that contains an open reading frame (ORF).Protein coding		B4DEC9	-	A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000509545.1	GRK4-007	831	No protein	Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript		-	-	-
ENST00000511827.1	GRK4-006	614	No protein	Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript		-	-	-
ENST00000505271.1	GRK4-009	515	No protein	Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript		-	-	-
ENST00000504308.1	GRK4-008	428	No protein	Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript		-	-	-
ENST00000507230.1	GRK4-011	394	No protein	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron		-	-	-

Summary

Name

GRK4 (HGNC Symbol)

UniProtKB

This gene has proteins that correspond to the following UniProtKB identifiers: P32298

CCDS

This gene is a member of the Human CCDS set: CCDS33946.1, CCDS33947.1, CCDS47002.1, CCDS68656.1

Ensembl version

ENSG00000125388.15

Other assemblies

This gene maps to 2,963,608-3,040,747 in GRCh38 coordinates.

Gene type

Protein coding

Annotation method

Annotation for this gene includes both automatic annotation from Ensembl and Havana manual curation, see article.

Alternative genes

This gene corresponds to the following database identifiers:

Havana gene:	OTTHUMG00000159914 (version 4)

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Gene: GRK4 ENSG00000125388

Summary