Gene: PIK3CA ENSG00000121879

Description

phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha [Source:HGNC Symbol;Acc:8975]

Gene Synonyms

CLOVE, CWS5, MCAP, MCM, MCMTC, PI3K, p110-alpha

Location

GRCh37:CM000665.1

About this gene

This gene has 4 transcripts (splice variants), 7 paralogues and is associated with 175 phenotypes.

Transcripts

Transcript ID	Name	bp	Protein	Translation ID	Biotype	CCDS	UniProt Match	RefSeq	Flags
ENST00000263967.3	PIK3CA-001	9093	1068aa	ENSP00000263967.3	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS43171	C9J951 C9JAM9 P42336 Q4LE51	NM_006218.2	A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, The GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).GENCODE basic,
ENST00000468036.1	PIK3CA-003	620	118aa	ENSP00000417479.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding		C9J951 C9JAM9	-	3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete,
ENST00000477735.1	PIK3CA-002	245	21aa	ENSP00000418145.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding		C9J951	-	3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete,
ENST00000462255.1	PIK3CA-004	746	No protein	-	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron		-	-	-

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