Gene: RPS6KA2 ENSG00000071242

Description

ribosomal protein S6 kinase, 90kDa, polypeptide 2 [Source:HGNC Symbol;Acc:10431]

Gene Synonyms

HU-2, MAPKAPK1C, RSK, RSK3, S6K-alpha, S6K-alpha2, p90-RSK3, pp90RSK3

Location

Chromosome 6: 166,822,852-167,319,939 reverse strand.

GRCh37:CM000668.1

About this gene

This gene has 14 transcripts (splice variants) and 10 paralogues.

Transcripts

Show transcript tableHide transcript table

Transcript ID	Name	bp	Protein	Biotype	CCDS	UniProt Match	RefSeq	Flags
ENST00000503859.1	RPS6KA2-003	4137	741aa	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS34570	B7Z3B5 D6R910 D6RD75 D6RHW7 Q15349	NM_001006932.1	A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000510118.1	RPS6KA2-005	5992	758aa	Gene/transcipt that contains an open reading frame (ORF).Protein coding		B7Z3B5 D6R910 D6RD75 D6RE03 D6RHW7 F2Z2J1	-	A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000265678.4	RPS6KA2-001	5824	733aa	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS5294	B7Z3B5 D6R910 D6RD75 D6RHW7 Q15349	NM_021135.4	A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000481261.2	RPS6KA2-006	2297	644aa	Gene/transcipt that contains an open reading frame (ORF).Protein coding		B7Z3B5 D6R910 D6RD75 D6RHW7	-	A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000405189.3	RPS6KA2-007	2282	644aa	Gene/transcipt that contains an open reading frame (ORF).Protein coding		B7Z3B5 D6R910 D6RD75 D6RHW7	-	A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000366863.2	RPS6KA2-201	1181	166aa	Gene/transcipt that contains an open reading frame (ORF).Protein coding		Q5TI62	-	A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000507371.1	RPS6KA2-011	759	141aa	Gene/transcipt that contains an open reading frame (ORF).Protein coding		D6RA62 D6RD75	-	3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete,
ENST00000511034.1	RPS6KA2-012	614	36aa	Gene/transcipt that contains an open reading frame (ORF).Protein coding		D6RD75	-	3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete,
ENST00000507350.1	RPS6KA2-013	596	125aa	Gene/transcipt that contains an open reading frame (ORF).Protein coding		D6R910 D6RD75 D6RHW7	-	3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete,
ENST00000506565.1	RPS6KA2-009	587	171aa	Gene/transcipt that contains an open reading frame (ORF).Protein coding		D6RD75 D6RE03	-	3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete,
ENST00000512860.1	RPS6KA2-010	552	96aa	Gene/transcipt that contains an open reading frame (ORF).Protein coding		D6RD75 D6RHW7	-	3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete,
ENST00000509742.1	RPS6KA2-008	1204	No protein	Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript		-	-	-
ENST00000491836.2	RPS6KA2-004	817	No protein	Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript		-	-	-
ENST00000366865.1	RPS6KA2-002	676	No protein	Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript		-	-	-

Summary

Name

RPS6KA2 (HGNC Symbol)

UniProtKB

This gene has proteins that correspond to the following UniProtKB identifiers: Q15349

CCDS

This gene is a member of the Human CCDS set: CCDS34570.1, CCDS5294.1

Ensembl version

ENSG00000071242.7

Other assemblies

This gene maps to 166,409,364-166,906,451 in GRCh38 coordinates.

Gene type

Protein coding

Annotation method

Annotation for this gene includes both automatic annotation from Ensembl and Havana manual curation, see article.

Alternative genes

This gene corresponds to the following database identifiers:

Havana gene:	OTTHUMG00000016007 (version 8)

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Gene: RPS6KA2 ENSG00000071242

Summary