Gene: ITGA2B ENSG00000005961

Description

integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41) [Source:HGNC Symbol;Acc:6138]

Gene Synonyms

BDPLT16, BDPLT2, CD41, CD41B, GP2B, GPIIb, GT, GTA, HPA3, ITGAB

Location

Chromosome 17: 42,449,548-42,466,873 reverse strand.

GRCh37:CM000679.1

About this gene

This gene has 12 transcripts (splice variants), 190 orthologues, 17 paralogues and is associated with 5 phenotypes.

Transcripts

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Transcript ID	Name	bp	Protein	Translation ID	Biotype	CCDS	UniProt Match	RefSeq	Flags
ENST00000262407.5	ITGA2B-001	3333	1039aa	ENSP00000262407.5	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS32665	F1C626 I6XCH0 P08514 Q6LDK5	NM_000419.3	A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000353281.4	ITGA2B-201	3232	1005aa	ENSP00000340536.4	Gene/transcipt that contains an open reading frame (ORF).Protein coding		F1C626 I6XCH0 P08514	-	A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000377068.3	ITGA2B-202	1212	219aa	ENSP00000366268.3	Gene/transcipt that contains an open reading frame (ORF).Protein coding		B7Z8B0	-	A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000587295.1	ITGA2B-011	496	104aa	ENSP00000467269.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding		-	-	5' truncation in transcript evidence prevents annotation of the start of the CDS.CDS 5' incomplete,
ENST00000588098.1	ITGA2B-012	281	32aa	ENSP00000465534.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding		-	-	5' truncation in transcript evidence prevents annotation of the start of the CDS.CDS 5' incomplete,
ENST00000592462.1	ITGA2B-003	3189	No protein	-	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron		-	-	-
ENST00000592226.1	ITGA2B-004	1170	No protein	-	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron		-	-	-
ENST00000589645.1	ITGA2B-009	579	No protein	-	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron		-	-	-
ENST00000591990.1	ITGA2B-007	565	No protein	-	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron		-	-	-
ENST00000592944.1	ITGA2B-005	563	No protein	-	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron		-	-	-
ENST00000592253.1	ITGA2B-006	462	No protein	-	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron		-	-	-
ENST00000592075.1	ITGA2B-008	461	No protein	-	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron		-	-	-

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Gene: ITGA2B ENSG00000005961

Summary