Gene: PTPN6 ENSG00000268954

Description

protein tyrosine phosphatase, non-receptor type 6 [Source:HGNC Symbol;Acc:9658]

Gene Synonyms

HCP, HCPH, HPTP1C, PTP-1C, PTP1C, SH-PTP1, SHP-1, SHP-1L, SHP1

Location

Chromosome HG344_PATCH: 7,055,631-7,070,479 forward strand.

GRCh37:JH720444.2

View this gene on the primary assembly.

About this gene

This gene has 24 transcripts (splice variants) and 1 gene allele.

Transcripts

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Transcript ID	Name	bp	Protein	Biotype	UniProt Match	RefSeq	Flags
ENST00000594686.1	PTPN6-203	2389	624aa	Gene/transcipt that contains an open reading frame (ORF).Protein coding	F5H0N8 P29350	-	A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000595623.1	PTPN6-008	2245	595aa	Gene/transcipt that contains an open reading frame (ORF).Protein coding	F5H0N8 P29350	-	A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000595832.1	PTPN6-001	2159	597aa	Gene/transcipt that contains an open reading frame (ORF).Protein coding	P29350 Q53XS4	-	A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000599028.1	PTPN6-204	1971	556aa	Gene/transcipt that contains an open reading frame (ORF).Protein coding	P29350	-	A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000601360.1	PTPN6-018	650	130aa	Gene/transcipt that contains an open reading frame (ORF).Protein coding	F5H5H9	-	3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete,
ENST00000594603.1	PTPN6-023	592	150aa	Gene/transcipt that contains an open reading frame (ORF).Protein coding	F5H1Z8	-	3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete,
ENST00000601126.1	PTPN6-014	579	165aa	Gene/transcipt that contains an open reading frame (ORF).Protein coding	F5H0N8	-	3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete,
ENST00000593615.1	PTPN6-021	570	144aa	Gene/transcipt that contains an open reading frame (ORF).Protein coding	F5GY79	-	3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete,
ENST00000597200.1	PTPN6-012	959	72aa	Nonsense mediated decay	U3KQS1	-	-
ENST00000595104.1	PTPN6-019	656	58aa	Nonsense mediated decay	F5H4Z1	-	-
ENST00000601810.1	PTPN6-013	602	56aa	Nonsense mediated decay	F5H1V7	-	-
ENST00000595466.1	PTPN6-016	543	60aa	Nonsense mediated decay	F5GXD4	-	-
ENST00000597701.1	PTPN6-004	705	No protein	Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript	-	-	-
ENST00000600874.1	PTPN6-005	673	No protein	Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript	-	-	-
ENST00000596654.1	PTPN6-007	664	No protein	Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript	-	-	-
ENST00000596748.1	PTPN6-011	592	No protein	Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript	-	-	-
ENST00000600151.1	PTPN6-010	564	No protein	Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript	-	-	-
ENST00000601527.1	PTPN6-025	538	No protein	Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript	-	-	-
ENST00000600446.1	PTPN6-003	2412	No protein	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron	-	-	-
ENST00000596084.1	PTPN6-002	2043	No protein	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron	-	-	-
ENST00000600931.1	PTPN6-022	907	No protein	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron	-	-	-
ENST00000595340.1	PTPN6-006	795	No protein	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron	-	-	-
ENST00000598477.1	PTPN6-024	759	No protein	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron	-	-	-
ENST00000594402.1	PTPN6-015	513	No protein	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron	-	-	-

Regulation

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Gene: PTPN6 ENSG00000268954

Regulation