Summary
- Splice variants
- Transcript comparison
- Gene alleles
Sequence
- Secondary Structure
Comparative Genomics
Ontologies
Phenotypes
Genetic Variation
Gene expression
Pathway
Molecular interactions
Regulation
External references
Supporting evidence
ID History
- Gene history

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Gene: IKZF3 ENSG00000161405

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Description

IKAROS family zinc finger 3 (Aiolos) [Source:HGNC Symbol;Acc:13178]

Gene Synonyms

AIO, AIOLOS, Aiolos, RP11-94L15.2, ZNFN1A3

Location

Chromosome 17: 37,921,198-38,020,441 reverse strand.

GRCh37:CM000679.1

About this gene

This gene has 16 transcripts (splice variants), 4 paralogues and is associated with 56 phenotypes.

Transcripts

Show transcript tableHide transcript table

Transcript ID	Name	bp	Protein	Biotype	CCDS	UniProt Match	RefSeq	Flags
ENST00000346872.3	IKZF3-001	2437	509aa	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS11346	B4DVV5 Q9UKT9	NM_012481.4	A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000535189.1	IKZF3-013	1996	475aa	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS58540	B4DVV5 Q9UKT9	NM_001257408.1	A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000439167.2	IKZF3-002	1879	436aa	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS58539	B4DVV5 Q9UKT9	NM_001257409.1	A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000377958.2	IKZF3-012	1837	422aa	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS58544	B4DVV5 Q9UKT9	NM_001257410.1	A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000377945.3	IKZF3-009	1696	375aa	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS58545	Q9UKT9	NM_001257414.1	A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000377944.3	IKZF3-011	1669	366aa	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS58543	B4DVV5 Q9UKT9	NM_001257411.1	A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000394189.2	IKZF3-010	1552	327aa	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS58542	B4DVV5 Q9UKT9	NM_001257412.1	A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000583368.1	IKZF3-016	1456	262aa	Gene/transcipt that contains an open reading frame (ORF).Protein coding		B4DVV5	-	A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000377952.2	IKZF3-014	1435	288aa	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS58541	Q9UKT9	NM_001257413.1	A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000351680.3	IKZF3-003	1413	470aa	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS11348	B4DVV5 Q9UKT9	NM_183229.2	A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000350532.3	IKZF3-005	1413	470aa	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS11349	Q9UKT9	NM_183230.2	A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000467757.1	IKZF3-006	1362	453aa	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS11347	B4DVV5 Q9UKT9	NM_183228.2	A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000346243.3	IKZF3-004	1296	431aa	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS11351	Q9UKT9	NM_183232.2	A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000439016.2	IKZF3-015	1246	414aa	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS11350	B4DVV5 Q9UKT9	NM_183231.2	A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000293068.5	IKZF3-008	2224	263aa	Nonsense mediated decay		Q9UKT9	-	-
ENST00000348427.3	IKZF3-007	2056	207aa	Nonsense mediated decay		Q9UKT9	-	-

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GO: Molecular function

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Accession	Term	Evidence	Annotation source	Transcript IDs
GO:0003700	sequence-specific DNA binding transcription factor activity	Traceable Author StatementTAS	Generated via main	ENST00000377945 ENST00000439016 ENST00000293068 ENST00000467757 ENST00000351680 ENST00000377958 ENST00000377952 ENST00000439167 ENST00000394189 ENST00000377944 ENST00000348427 ENST00000535189 ENST00000346872 ENST00000350532 ENST00000346243	Search BioMart View on karyotype
GO:0005515	protein binding	Inferred from Physical InteractionIPI	Generated via main	ENST00000535189 ENST00000348427 ENST00000346872 ENST00000350532 ENST00000346243 ENST00000293068 ENST00000439016 ENST00000377945 ENST00000351680 ENST00000467757 ENST00000377958 ENST00000377952 ENST00000439167 ENST00000377944 ENST00000394189	Search BioMart View on karyotype
GO:0042803	protein homodimerization activity	Inferred from Direct AssayIDA	Generated via main	ENST00000346243 ENST00000350532 ENST00000346872 ENST00000535189 ENST00000348427 ENST00000439167 ENST00000377944 ENST00000394189 ENST00000377958 ENST00000377952 ENST00000351680 ENST00000467757 ENST00000293068 ENST00000439016 ENST00000377945	Search BioMart View on karyotype
GO:0043565	sequence-specific DNA binding	Inferred from Electronic AnnotationIEA	Generated via main	ENST00000348427 ENST00000535189 ENST00000346872 ENST00000350532 ENST00000346243 ENST00000293068 ENST00000377945 ENST00000439016 ENST00000351680 ENST00000467757 ENST00000377952 ENST00000377958 ENST00000583368 ENST00000377944 ENST00000394189 ENST00000439167	Search BioMart View on karyotype
GO:0046872	metal ion binding	Inferred from Electronic AnnotationIEA	Generated via main	ENST00000346243 ENST00000350532 ENST00000346872 ENST00000535189 ENST00000348427 ENST00000439167 ENST00000394189 ENST00000377944 ENST00000583368 ENST00000377958 ENST00000377952 ENST00000467757 ENST00000351680 ENST00000439016 ENST00000377945 ENST00000293068	Search BioMart View on karyotype
GO:0046982	protein heterodimerization activity	Inferred from Electronic AnnotationIEA	Generated via main	ENST00000346872 ENST00000350532 ENST00000535189 ENST00000348427 ENST00000346243 ENST00000351680 ENST00000467757 ENST00000293068 ENST00000377945 ENST00000439016 ENST00000377944 ENST00000394189 ENST00000439167 ENST00000377952 ENST00000377958 ENST00000583368	Search BioMart View on karyotype

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