Summary
- Splice variants
- Transcript comparison
- Gene alleles
Sequence
- Secondary Structure
Comparative Genomics
Ontologies
Phenotypes
Genetic Variation
Gene expression
Pathway
Molecular interactions
Regulation
External references
Supporting evidence
ID History
- Gene history

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Gene: PRKACA ENSG00000072062

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Description

protein kinase, cAMP-dependent, catalytic, alpha [Source:HGNC Symbol;Acc:9380]

Gene Synonyms

PKACA, PKACa

Location

Chromosome 19: 14,202,500-14,228,896 reverse strand.

GRCh37:CM000681.1

About this gene

This gene has 10 transcripts (splice variants), 5 paralogues and is associated with 49 phenotypes.

Transcripts

Show transcript tableHide transcript table

Transcript ID	Name	bp	Protein	Biotype	CCDS	UniProt Match	RefSeq	Flags
ENST00000308677.4	PRKACA-001	2677	351aa	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS12304	K7EMV1 P17612	NM_002730.3	A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000589994.1	PRKACA-003	1127	343aa	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS12305	K7EMV1 P17612	NM_207518.1	A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000590853.1	PRKACA-002	1101	124aa	Gene/transcipt that contains an open reading frame (ORF).Protein coding		K7ENJ5	-	A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000593092.1	PRKACA-006	922	207aa	Gene/transcipt that contains an open reading frame (ORF).Protein coding		K7EMV1 Q15136	-	5' truncation in transcript evidence prevents annotation of the start of the CDS.CDS 5' incomplete,
ENST00000587372.1	PRKACA-010	824	251aa	Gene/transcipt that contains an open reading frame (ORF).Protein coding		K7EMV1	-	5' truncation in transcript evidence prevents annotation of the start of the CDS.CDS 5' incomplete,
ENST00000589284.1	PRKACA-008	403	25aa	Gene/transcipt that contains an open reading frame (ORF).Protein coding		K7EMV1	-	3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete,
ENST00000350356.3	PRKACA-005	3105	No protein	Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript		-	-	-
ENST00000587533.1	PRKACA-007	2095	No protein	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron		-	-	-
ENST00000536649.1	PRKACA-004	1524	No protein	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron		-	-	-
ENST00000588209.1	PRKACA-009	942	No protein	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron		-	-	-

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GO: Cellular component

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Accession	Term	Evidence	Annotation source	Transcript IDs
GO:0005634	nucleus	Inferred from Electronic AnnotationIEA	Generated via main	ENST00000593092 ENST00000587372 ENST00000589284 ENST00000589994 ENST00000308677	Search BioMart View on karyotype
GO:0005737	cytoplasm	Inferred from Electronic AnnotationIEA	Ensembl	ENST00000308677	Search BioMart View on karyotype
GO:0005739	mitochondrion	Inferred from Electronic AnnotationIEA	Generated via main	ENST00000589284 ENST00000308677 ENST00000589994 ENST00000587372 ENST00000593092	Search BioMart View on karyotype
GO:0005813	centrosome	Inferred from Direct AssayIDA	Generated via main	ENST00000308677 ENST00000589994	Search BioMart View on karyotype
GO:0005829	cytosol	Traceable Author StatementTAS	Generated via main	ENST00000589994 ENST00000308677	Search BioMart View on karyotype
GO:0005886	plasma membrane	Inferred from Electronic AnnotationIEA	Generated via main	ENST00000589284 ENST00000308677 ENST00000589994 ENST00000593092 ENST00000587372	Search BioMart View on karyotype
GO:0005929	cilium	Inferred from Electronic AnnotationIEA	Generated via main	ENST00000589994 ENST00000308677	Search BioMart View on karyotype
GO:0005952	cAMP-dependent protein kinase complex	Non-traceable Author StatementNAS	Generated via main	ENST00000589994 ENST00000308677	Search BioMart View on karyotype
GO:0016020	membrane	Inferred from Direct AssayIDA	Generated via main	ENST00000308677 ENST00000589994	Search BioMart View on karyotype
GO:0031588	AMP-activated protein kinase complex	Inferred from Direct AssayIDA	Generated via main	ENST00000589994 ENST00000308677	Search BioMart View on karyotype
GO:0031594	neuromuscular junction	Inferred from Electronic AnnotationIEA	Generated via main	ENST00000593092 ENST00000587372 ENST00000589994 ENST00000308677 ENST00000589284	Search BioMart View on karyotype
GO:0034704	calcium channel complex	Traceable Author StatementTAS	Generated via main	ENST00000308677 ENST00000589994	Search BioMart View on karyotype
GO:0097225	sperm midpiece	Inferred from Direct AssayIDA	Generated via main	ENST00000589994 ENST00000308677	Search BioMart View on karyotype

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