Human (GRCh37.p13)
Description

BCL2-like 1 [Source:HGNC Symbol;Acc:992]

Gene Synonyms

BCL-XL/S, BCL2L, BCLX, BCLXL, BCLXS, Bcl-X, PPP1R52, bcl-xL, bcl-xS

Location

Chromosome 20: 30,252,255-30,311,792 reverse strand.

GRCh37:CM000682.1

About this gene

This gene has 10 transcripts (splice variants) and 3 paralogues.

Show/hide columns (1 hidden)
  • Transcript ID
  • Name
  • bp
  • Protein
  • Translation ID
  • Biotype
  • CCDS
  • UniProt Match
  • RefSeq
  • Flags
Transcript IDNamebpProteinBiotypeCCDSUniProt MatchRefSeqFlags
ENST00000307677.4BCL2L1-0042610233aa
 
Protein coding
CCDS13189Q07817 Q5QP56 Q5QP59
Q5TE64 Q9H1R6
NM_138578.1Ensembl CanonicalGENCODE Basic
ENST00000420653.1BCL2L1-2012588233aa
 
Protein coding
CCDS13189Q07817 Q5QP56 Q5QP59
Q5TE64 Q9H1R6
-GENCODE Basic
ENST00000376062.2BCL2L1-0012578233aa
 
Protein coding
CCDS13189Q07817 Q5QP56 Q5QP59
Q5TE64 Q9H1R6
-GENCODE Basic
ENST00000376055.4BCL2L1-0022383170aa
 
Protein coding
CCDS13188Q07817 Q5QP59 Q5TE63
NM_001191.2GENCODE Basic
ENST00000422920.1BCL2L1-0081157188aa
 
Protein coding
Q5QP56 Q5QP59 Q9H1R6
-CDS 3' incomplete
ENST00000456404.1BCL2L1-007914188aa
 
Protein coding
Q5QP56 Q5QP59 Q9H1R6
-CDS 3' incomplete
ENST00000450273.1BCL2L1-003894205aa
 
Protein coding
Q5QP56 Q5QP59 Q5TE64
Q9H1R6
-CDS 3' incomplete
ENST00000420488.1BCL2L1-006820188aa
 
Protein coding
Q5QP56 Q5QP59 Q9H1R6
-CDS 3' incomplete
ENST00000439267.1BCL2L1-005781181aa
 
Protein coding
Q5QP56 Q5QP59 -CDS 3' incomplete
ENST00000434194.1BCL2L1-00938148aa
 
Protein coding
Q5QP59 -CDS 3' incomplete
    Show/hide columns (1 hidden)
    • Accession
    • Term
    • Evidence
    • Annotation source
    • Mapped using
    • Transcript IDs
    AccessionTermEvidenceAnnotation sourceTranscript IDs
    GO:0000910cytokinesisIMPGenerated via mainENST00000307677
    ENST00000420653
    ENST00000376055
    ENST00000376062
    GO:0001541ovarian follicle developmentIEAGenerated via mainENST00000434194
    ENST00000420653
    ENST00000376062
    ENST00000456404
    ENST00000450273
    ENST00000439267
    ENST00000420488
    ENST00000422920
    ENST00000376055
    ENST00000307677
    GO:0001701in utero embryonic developmentIEAGenerated via mainENST00000420653
    ENST00000434194
    ENST00000376062
    ENST00000450273
    ENST00000456404
    ENST00000439267
    ENST00000422920
    ENST00000420488
    ENST00000376055
    ENST00000307677
    GO:0001836release of cytochrome c from mitochondriaIEAGenerated via mainENST00000307677
    ENST00000422920
    ENST00000420488
    ENST00000376055
    ENST00000456404
    ENST00000450273
    ENST00000439267
    ENST00000420653
    ENST00000434194
    ENST00000376062
    GO:0006897endocytosisIEAGenerated via mainENST00000376062
    ENST00000420653
    ENST00000376055
    ENST00000307677
    GO:0006915apoptotic processTASGenerated via mainENST00000376055
    ENST00000307677
    ENST00000420653
    ENST00000376062
    GO:0007093mitotic cell cycle checkpointIMPGenerated via mainENST00000420653
    ENST00000376062
    ENST00000307677
    ENST00000376055
    GO:0007281germ cell developmentIEAGenerated via mainENST00000307677
    ENST00000422920
    ENST00000420488
    ENST00000376055
    ENST00000450273
    ENST00000456404
    ENST00000439267
    ENST00000434194
    ENST00000420653
    ENST00000376062
    GO:0007283spermatogenesisIEAGenerated via mainENST00000376062
    ENST00000420653
    ENST00000434194
    ENST00000439267
    ENST00000450273
    ENST00000456404
    ENST00000422920
    ENST00000420488
    ENST00000376055
    ENST00000307677
    GO:0008283cell proliferationIEAGenerated via mainENST00000420653
    ENST00000434194
    ENST00000376062
    ENST00000456404
    ENST00000450273
    ENST00000439267
    ENST00000376055
    ENST00000420488
    ENST00000422920
    ENST00000307677
    GO:0008284positive regulation of cell proliferationIEAGenerated via mainENST00000307677
    ENST00000376055
    ENST00000420488
    ENST00000422920
    ENST00000450273
    ENST00000456404
    ENST00000439267
    ENST00000434194
    ENST00000420653
    ENST00000376062
    GO:0008584male gonad developmentIEAGenerated via mainENST00000456404
    ENST00000450273
    ENST00000439267
    ENST00000434194
    ENST00000420653
    ENST00000376062
    ENST00000307677
    ENST00000422920
    ENST00000420488
    ENST00000376055
    GO:0008630intrinsic apoptotic signaling pathway in response to DNA damageIEAEnsemblENST00000307677
    GO:0008637apoptotic mitochondrial changesTASGenerated via mainENST00000376055
    ENST00000307677
    ENST00000376062
    ENST00000420653
    GO:0009314response to radiationIEAEnsemblENST00000307677
    GO:0009566fertilizationIEAGenerated via mainENST00000307677
    ENST00000376055
    ENST00000420488
    ENST00000422920
    ENST00000439267
    ENST00000456404
    ENST00000450273
    ENST00000376062
    ENST00000420653
    ENST00000434194
    GO:0009615response to virusIEAEnsemblENST00000307677
    GO:0010507negative regulation of autophagyTASGenerated via mainENST00000420653
    ENST00000376062
    ENST00000376055
    ENST00000307677
    GO:0019050suppression by virus of host apoptotic processIDAGenerated via mainENST00000376055
    ENST00000307677
    ENST00000420653
    ENST00000376062
    GO:0034097response to cytokineIDAGenerated via mainENST00000420653
    ENST00000376062
    ENST00000307677
    ENST00000376055
    GO:0035872nucleotide-binding domain, leucine rich repeat containing receptor signaling pathwayTASGenerated via mainENST00000307677
    ENST00000376055
    ENST00000420653
    ENST00000376062
    GO:0040007growthIEAGenerated via mainENST00000376062
    ENST00000434194
    ENST00000420653
    ENST00000439267
    ENST00000450273
    ENST00000456404
    ENST00000376055
    ENST00000420488
    ENST00000422920
    ENST00000307677
    GO:0042981regulation of apoptotic processIEAGenerated via mainENST00000420653
    ENST00000434194
    ENST00000376062
    ENST00000456404
    ENST00000450273
    ENST00000439267
    ENST00000422920
    ENST00000420488
    ENST00000376055
    ENST00000307677
    GO:0043065positive regulation of apoptotic processIEAGenerated via mainENST00000307677
    ENST00000420488
    ENST00000376055
    ENST00000422920
    ENST00000450273
    ENST00000456404
    ENST00000439267
    ENST00000434194
    ENST00000420653
    ENST00000376062
    GO:0043066negative regulation of apoptotic processIMPGenerated via mainENST00000420653
    ENST00000376062
    ENST00000376055
    ENST00000307677
    GO:0043524negative regulation of neuron apoptotic processIEAGenerated via mainENST00000307677
    ENST00000376055
    ENST00000420488
    ENST00000422920
    ENST00000439267
    ENST00000456404
    ENST00000450273
    ENST00000376062
    ENST00000434194
    ENST00000420653
    GO:0045087innate immune responseTASGenerated via mainENST00000307677
    ENST00000376055
    ENST00000376062
    ENST00000420653
    GO:0046898response to cycloheximideIEAGenerated via mainENST00000307677
    ENST00000422920
    ENST00000420488
    ENST00000376055
    ENST00000439267
    ENST00000450273
    ENST00000456404
    ENST00000376062
    ENST00000420653
    ENST00000434194
    GO:0046902regulation of mitochondrial membrane permeabilityIDAGenerated via mainENST00000420653
    ENST00000376062
    ENST00000376055
    ENST00000307677
    GO:0051402neuron apoptotic processIEAEnsemblENST00000307677
    GO:0051881regulation of mitochondrial membrane potentialIDAGenerated via mainENST00000420653
    ENST00000376062
    ENST00000307677
    ENST00000376055
    GO:0060154cellular process regulating host cell cycle in response to virusIEAGenerated via mainENST00000434194
    ENST00000420653
    ENST00000376062
    ENST00000450273
    ENST00000456404
    ENST00000439267
    ENST00000420488
    ENST00000422920
    ENST00000376055
    ENST00000307677
    GO:0071230cellular response to amino acid stimulusIEAGenerated via mainENST00000376055
    ENST00000420488
    ENST00000422920
    ENST00000307677
    ENST00000434194
    ENST00000420653
    ENST00000376062
    ENST00000450273
    ENST00000456404
    ENST00000439267
    GO:0071312cellular response to alkaloidIEAGenerated via mainENST00000376062
    ENST00000434194
    ENST00000420653
    ENST00000439267
    ENST00000456404
    ENST00000450273
    ENST00000376055
    ENST00000420488
    ENST00000422920
    ENST00000307677
    GO:0071480cellular response to gamma radiationIEAGenerated via mainENST00000376062
    ENST00000434194
    ENST00000420653
    ENST00000439267
    ENST00000456404
    ENST00000450273
    ENST00000420488
    ENST00000422920
    ENST00000376055
    ENST00000307677
    GO:0071839apoptotic process in bone marrowIEAEnsemblENST00000307677
    GO:0090005negative regulation of establishment of protein localization to plasma membraneIDAGenerated via mainENST00000376062
    ENST00000420653
    ENST00000376055
    ENST00000307677
    GO:0090201negative regulation of release of cytochrome c from mitochondriaIDAGenerated via mainENST00000376062
    ENST00000420653
    ENST00000307677
    ENST00000376055
    GO:0097192extrinsic apoptotic signaling pathway in absence of ligandIBAGenerated via mainENST00000376062
    ENST00000420653
    ENST00000376055
    ENST00000307677
    GO:0097193intrinsic apoptotic signaling pathwayTASGenerated via mainENST00000307677
    ENST00000376055
    ENST00000420653
    ENST00000376062
    GO:0097284hepatocyte apoptotic processIEAEnsemblENST00000307677
    GO:1900118negative regulation of execution phase of apoptosisIDAGenerated via mainENST00000376055
    ENST00000307677
    ENST00000420653
    ENST00000376062
    GO:1902230negative regulation of intrinsic apoptotic signaling pathway in response to DNA damageIDAGenerated via mainENST00000376055
    ENST00000307677
    ENST00000376062
    ENST00000420653
    GO:2000811negative regulation of anoikisIMPGenerated via mainENST00000376055
    ENST00000307677
    ENST00000376062
    ENST00000420653
    GO:2001240negative regulation of extrinsic apoptotic signaling pathway in absence of ligandTASGenerated via mainENST00000376062
    ENST00000420653
    ENST00000376055
    ENST00000307677
    GO:2001243negative regulation of intrinsic apoptotic signaling pathwayIDAGenerated via mainENST00000376055
    ENST00000307677
    ENST00000376062
    ENST00000420653
    GO:2001244positive regulation of intrinsic apoptotic signaling pathwayTASGenerated via mainENST00000420653
    ENST00000376062
    ENST00000376055
    ENST00000307677