Gene: PTPN6 ENSG00000111679

Description

protein tyrosine phosphatase, non-receptor type 6 [Source:HGNC Symbol;Acc:9658]

Gene Synonyms

HCP, HCPH, HPTP1C, PTP-1C, PTP1C, SH-PTP1, SHP-1, SHP-1L, SHP1

Location

Chromosome 12: 7,055,631-7,070,479 forward strand.

GRCh37:CM000674.1

View alleles of this gene on alternative sequences

About this gene

This gene has 24 transcripts (splice variants), 1 gene allele, 13 paralogues and is associated with 48 phenotypes.

Transcripts

Show transcript tableHide transcript table

Transcript ID	Name	bp	Protein	Biotype	CCDS	UniProt Match	RefSeq	Flags
ENST00000456013.1	PTPN6-202	2389	624aa	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS44821	F5H0N8 P29350	NM_080549.3	A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000318974.9	PTPN6-008	2245	595aa	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS44820	F5H0N8 P29350	NM_002831.5	A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000399448.1	PTPN6-001	2159	597aa	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS41744	P29350 Q53XS4	NM_080548.4	A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000447931.2	PTPN6-201	1971	556aa	Gene/transcipt that contains an open reading frame (ORF).Protein coding		P29350	-	A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000543115.1	PTPN6-018	650	130aa	Gene/transcipt that contains an open reading frame (ORF).Protein coding		F5H5H9	-	3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete,
ENST00000541698.1	PTPN6-023	592	150aa	Gene/transcipt that contains an open reading frame (ORF).Protein coding		F5H1Z8	-	3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete,
ENST00000538715.1	PTPN6-014	579	165aa	Gene/transcipt that contains an open reading frame (ORF).Protein coding		F5H0N8	-	3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete,
ENST00000542462.1	PTPN6-021	570	144aa	Gene/transcipt that contains an open reading frame (ORF).Protein coding		F5GY79	-	3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete,
ENST00000545153.1	PTPN6-012	959	72aa	Nonsense mediated decay		U3KQS1	-	-
ENST00000542848.1	PTPN6-019	656	58aa	Nonsense mediated decay		F5H4Z1	-	-
ENST00000536013.1	PTPN6-013	602	56aa	Nonsense mediated decay		F5H1V7	-	-
ENST00000535462.1	PTPN6-016	543	60aa	Nonsense mediated decay		F5GXD4	-	-
ENST00000539029.1	PTPN6-004	705	No protein	Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript		-	-	-
ENST00000537533.1	PTPN6-005	673	No protein	Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript		-	-	-
ENST00000542277.1	PTPN6-007	664	No protein	Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript		-	-	-
ENST00000540740.1	PTPN6-011	592	No protein	Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript		-	-	-
ENST00000543120.1	PTPN6-010	564	No protein	Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript		-	-	-
ENST00000534900.1	PTPN6-025	538	No protein	Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript		-	-	-
ENST00000416215.2	PTPN6-003	2412	No protein	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron		-	-	-
ENST00000543744.1	PTPN6-002	2043	No protein	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron		-	-	-
ENST00000539365.1	PTPN6-022	907	No protein	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron		-	-	-
ENST00000542761.1	PTPN6-006	795	No protein	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron		-	-	-
ENST00000538318.1	PTPN6-024	759	No protein	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron		-	-	-
ENST00000536521.1	PTPN6-015	513	No protein	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron		-	-	-

Gene tree

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You can still view this page on the following archive resources:

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Gene: PTPN6 ENSG00000111679

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