Gene: SIRT1 ENSG00000096717

Description

sirtuin 1 [Source:HGNC Symbol;Acc:14929]

Gene Synonyms

SIR2L1

Location

Chromosome 10: 69,644,427-69,678,147 forward strand.

GRCh37:CM000672.1

About this gene

This gene has 6 transcripts (splice variants), 157 orthologues and 6 paralogues.

Transcripts

Show transcript tableHide transcript table

Transcript ID	Name	bp	Protein	Translation ID	Biotype	CCDS	UniProt Match	RefSeq	Flags
ENST00000212015.6	SIRT1-001	4094	747aa	ENSP00000212015.6	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS7273	A8K128 E9PC49 Q96EB6	NM_012238.4	A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000432464.1	SIRT1-201	3587	452aa	ENSP00000409208.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS44412	E9PC49	NM_001142498.1	A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000403579.1	SIRT1-003	3333	444aa	ENSP00000384063.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding		B0QZ35	-	A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000406900.1	SIRT1-002	3295	444aa	ENSP00000384508.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding		B0QZ35	-	A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000497639.1	SIRT1-005	673	No protein	-	Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript		-	-	-
ENST00000473922.1	SIRT1-004	576	No protein	-	Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript		-	-	-

Gene tree

As of the latest update in March 2020 we are not supporting data for species other than human on this GRCh37 site and the view you wish to use is disabled.

You can read more about why we have done this on our blog.

You can still view this page on the following archive resources:

1. The Ensembl 75 archive represents a code and data freeze taken in February 2014.

2. The GRCh37 archive represents a code and data freeze taken in January 2019.

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Gene: SIRT1 ENSG00000096717

Gene tree