Summary
- Splice variants
- Transcript comparison
- Gene alleles
Sequence
- Secondary Structure
Comparative Genomics
Ontologies
Phenotypes
Genetic Variation
Gene expression
Pathway
Molecular interactions
Regulation
External references
Supporting evidence
ID History
- Gene history

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Gene: FCGR3B ENSG00000162747

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Description

Fc fragment of IgG, low affinity IIIb, receptor (CD16b) [Source:HGNC Symbol;Acc:3620]

Gene Synonyms

CD16, CD16B, CD16b, FCG3, FCGR3, FCR-10, FCRIII, FCRIIIb, IGFR3

Location

Chromosome 1: 161,592,986-161,601,753 reverse strand.

GRCh37:CM000663.1

About this gene

This gene has 7 transcripts (splice variants), 14 paralogues and is associated with 2 phenotypes.

Transcripts

Show transcript tableHide transcript table

Transcript ID	Name	bp	Protein	Biotype	CCDS	UniProt Match	RefSeq	Flags
ENST00000531221.1	FCGR3B-001	1339	269aa	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS58040	E9PNY5 M9MML6	-	A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000294800.3	FCGR3B-201	2289	233aa	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS41433	E9PNY5 O75015	NM_001271035.1	A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000367964.2	FCGR3B-003	2143	233aa	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS41433	E9PNY5 O75015	NM_001271036.1	A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000421702.2	FCGR3B-002	1055	254aa	Gene/transcipt that contains an open reading frame (ORF).Protein coding		-	-	5' truncation in transcript evidence prevents annotation of the start of the CDS.CDS 5' incomplete,
ENST00000534776.1	FCGR3B-005	584	104aa	Gene/transcipt that contains an open reading frame (ORF).Protein coding		E9PNY5	-	3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete,
ENST00000534489.1	FCGR3B-004	571	No protein	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron		-	-	-
ENST00000533780.1	FCGR3B-006	569	No protein	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron		-	-	-

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Paralogues

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Download paralogues

Type	Ancestral taxonomy	Ensembl identifier & gene name	Compare	Location	Percentage of the paralogous sequence matching the query sequenceTarget %id	Percentage of the query sequence matching the sequence of the paralogueQuery %id
Ancient paralogues	Last common ancestor with Ray-finned fishes (Neopterygii)Bony vertebrates (Euteleostomi)	ENSG00000160856 FCRL3 Fc receptor-like 3 [Source:HGNC Symbol;Acc:18506]	Alignment (protein) Alignment (cDNA)	1:157,644,111-157,670,647:-1	8.00 %	22.00 %
Ancient paralogues	Last common ancestor with Ray-finned fishes (Neopterygii)Bony vertebrates (Euteleostomi)	ENSG00000181036 FCRL6 Fc receptor-like 6 [Source:HGNC Symbol;Acc:31910]	Alignment (protein) Alignment (cDNA)	1:159,770,301-159,786,041:1	9.00 %	14.00 %
Ancient paralogues	Last common ancestor with Ray-finned fishes (Neopterygii)Bony vertebrates (Euteleostomi)	ENSG00000132704 FCRL2 Fc receptor-like 2 [Source:HGNC Symbol;Acc:14875]	Alignment (protein) Alignment (cDNA)	1:157,715,523-157,746,922:-1	8.00 %	16.00 %
Ancient paralogues	Last common ancestor with Ray-finned fishes (Neopterygii)Bony vertebrates (Euteleostomi)	ENSG00000163534 FCRL1 Fc receptor-like 1 [Source:HGNC Symbol;Acc:18509]	Alignment (protein) Alignment (cDNA)	1:157,764,193-157,789,895:-1	3.00 %	5.00 %
Ancient paralogues	Last common ancestor with Ray-finned fishes (Neopterygii)Bony vertebrates (Euteleostomi)	ENSG00000143297 FCRL5 Fc receptor-like 5 [Source:HGNC Symbol;Acc:18508]	Alignment (protein) Alignment (cDNA)	1:157,483,167-157,522,310:-1	7.00 %	24.00 %
Ancient paralogues	Last common ancestor with Ray-finned fishes (Neopterygii)Bony vertebrates (Euteleostomi)	ENSG00000163518 FCRL4 Fc receptor-like 4 [Source:HGNC Symbol;Acc:18507]	Alignment (protein) Alignment (cDNA)	1:157,543,539-157,567,870:-1	12.00 %	24.00 %
Ancient paralogues	Last common ancestor with Ray-finned fishes (Neopterygii)Bony vertebrates (Euteleostomi)	ENSG00000132185 FCRLA Fc receptor-like A [Source:HGNC Symbol;Acc:18504]	Alignment (protein) Alignment (cDNA)	1:161,676,762-161,684,142:1	13.00 %	19.00 %
Genes (homologues) that have evolved by duplication.Paralogues	Human	ENSG00000203747 FCGR3A Fc fragment of IgG, low affinity IIIa, receptor (CD16a) [Source:HGNC Symbol;Acc:3619]	Alignment (protein) Alignment (cDNA)	1:161,511,549-161,600,917:-1	90.00 %	97.00 %
Genes (homologues) that have evolved by duplication.Paralogues	Last common ancestor with Marsupials (Marsupialia)Marsupials and Placental mammals (Theria)	ENSG00000143226 FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32) [Source:HGNC Symbol;Acc:3616]	Alignment (protein) Alignment (cDNA)	1:161,475,220-161,493,803:1	33.00 %	39.00 %
Genes (homologues) that have evolved by duplication.Paralogues	Last common ancestor with Marsupials (Marsupialia)Marsupials and Placental mammals (Theria)	ENSG00000072694 FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32) [Source:HGNC Symbol;Acc:3618]	Alignment (protein) Alignment (cDNA)	1:161,551,101-161,648,444:1	33.00 %	38.00 %
Genes (homologues) that have evolved by duplication.Paralogues	Last common ancestor with Marsupials (Marsupialia)Marsupials and Placental mammals (Theria)	ENSG00000150337 FCGR1A Fc fragment of IgG, high affinity Ia, receptor (CD64) [Source:HGNC Symbol;Acc:3613]	Alignment (protein) Alignment (cDNA)	1:149,754,227-149,764,074:1	24.00 %	34.00 %
Genes (homologues) that have evolved by duplication.Paralogues	Last common ancestor with Marsupials (Marsupialia)Marsupials and Placental mammals (Theria)	ENSG00000198019 FCGR1B Fc fragment of IgG, high affinity Ib, receptor (CD64) [Source:HGNC Symbol;Acc:3614]	Alignment (protein) Alignment (cDNA)	1:120,926,979-120,935,937:-1	32.00 %	33.00 %
Genes (homologues) that have evolved by duplication.Paralogues	Last common ancestor with Platypus (Ornithorhynchus anatinus)Mammals (Mammalia)	ENSG00000179639 FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide [Source:HGNC Symbol;Acc:3609]	Alignment (protein) Alignment (cDNA)	1:159,259,504-159,278,014:1	35.00 %	33.00 %
Genes (homologues) that have evolved by duplication.Paralogues	Last common ancestor with Platypus (Ornithorhynchus anatinus)Mammals (Mammalia)	ENSG00000162746 FCRLB Fc receptor-like B [Source:HGNC Symbol;Acc:26431]	Alignment (protein) Alignment (cDNA)	1:161,691,353-161,697,933:1	16.00 %	25.00 %

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