Summary
- Splice variants
- Transcript comparison
- Gene alleles
Sequence
- Secondary Structure
Comparative Genomics
Ontologies
Phenotypes
Genetic Variation
Gene expression
Pathway
Molecular interactions
Regulation
External references
Supporting evidence
ID History
- Gene history

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Gene: FCGR3A ENSG00000203747

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Description

Fc fragment of IgG, low affinity IIIa, receptor (CD16a) [Source:HGNC Symbol;Acc:3619]

Gene Synonyms

CD16, CD16A, CD16a, FCG3, FCGR3, FCGRIII, FCR-10, FCRIII, FCRIIIA, IGFR3

Location

Chromosome 1: 161,511,549-161,600,917 reverse strand.

GRCh37:CM000663.1

About this gene

This gene has 8 transcripts (splice variants), 14 paralogues and is associated with 1 phenotype.

Transcripts

Show transcript tableHide transcript table

Transcript ID	Name	bp	Protein	Biotype	CCDS	UniProt Match	RefSeq	Flags
ENST00000367969.3	FCGR3A-001	2310	290aa	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS1232	M9MML0 Q9UN20	NM_000569.6	A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000443193.1	FCGR3A-202	2301	289aa	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS44265	C9JC71 E9PG94 Q9UN20	NM_001127592.1	A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000436743.1	FCGR3A-201	2167	254aa	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS44266	P08637 Q9UN20	NM_001127596.1	A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000367967.3	FCGR3A-003	2086	254aa	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS44266	P08637 Q9UN20	-	-
ENST00000426740.1	FCGR3A-005	1972	271aa	Gene/transcipt that contains an open reading frame (ORF).Protein coding		C9JC71 Q9UN20	-	5' truncation in transcript evidence prevents annotation of the start of the CDS.CDS 5' incomplete,
ENST00000540048.1	FCGR3A-203	887	254aa	Gene/transcipt that contains an open reading frame (ORF).Protein coding		P08637 Q9UN20	-	A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000442336.1	FCGR3A-004	462	105aa	Gene/transcipt that contains an open reading frame (ORF).Protein coding		C9JC71	-	3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete,
ENST00000476031.1	FCGR3A-002	691	No protein	Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript		-	-	-

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Paralogues

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Download paralogues

Type	Ancestral taxonomy	Ensembl identifier & gene name	Compare	Location	Percentage of the paralogous sequence matching the query sequenceTarget %id	Percentage of the query sequence matching the sequence of the paralogueQuery %id
Ancient paralogues	Last common ancestor with Ray-finned fishes (Neopterygii)Bony vertebrates (Euteleostomi)	ENSG00000160856 FCRL3 Fc receptor-like 3 [Source:HGNC Symbol;Acc:18506]	Alignment (protein) Alignment (cDNA)	1:157,644,111-157,670,647:-1	8.00 %	21.00 %
Ancient paralogues	Last common ancestor with Ray-finned fishes (Neopterygii)Bony vertebrates (Euteleostomi)	ENSG00000181036 FCRL6 Fc receptor-like 6 [Source:HGNC Symbol;Acc:31910]	Alignment (protein) Alignment (cDNA)	1:159,770,301-159,786,041:1	9.00 %	13.00 %
Ancient paralogues	Last common ancestor with Ray-finned fishes (Neopterygii)Bony vertebrates (Euteleostomi)	ENSG00000132704 FCRL2 Fc receptor-like 2 [Source:HGNC Symbol;Acc:14875]	Alignment (protein) Alignment (cDNA)	1:157,715,523-157,746,922:-1	8.00 %	15.00 %
Ancient paralogues	Last common ancestor with Ray-finned fishes (Neopterygii)Bony vertebrates (Euteleostomi)	ENSG00000163534 FCRL1 Fc receptor-like 1 [Source:HGNC Symbol;Acc:18509]	Alignment (protein) Alignment (cDNA)	1:157,764,193-157,789,895:-1	4.00 %	6.00 %
Ancient paralogues	Last common ancestor with Ray-finned fishes (Neopterygii)Bony vertebrates (Euteleostomi)	ENSG00000143297 FCRL5 Fc receptor-like 5 [Source:HGNC Symbol;Acc:18508]	Alignment (protein) Alignment (cDNA)	1:157,483,167-157,522,310:-1	7.00 %	23.00 %
Ancient paralogues	Last common ancestor with Ray-finned fishes (Neopterygii)Bony vertebrates (Euteleostomi)	ENSG00000163518 FCRL4 Fc receptor-like 4 [Source:HGNC Symbol;Acc:18507]	Alignment (protein) Alignment (cDNA)	1:157,543,539-157,567,870:-1	13.00 %	22.00 %
Ancient paralogues	Last common ancestor with Ray-finned fishes (Neopterygii)Bony vertebrates (Euteleostomi)	ENSG00000132185 FCRLA Fc receptor-like A [Source:HGNC Symbol;Acc:18504]	Alignment (protein) Alignment (cDNA)	1:161,676,762-161,684,142:1	14.00 %	19.00 %
Genes (homologues) that have evolved by duplication.Paralogues	Human	ENSG00000162747 FCGR3B Fc fragment of IgG, low affinity IIIb, receptor (CD16b) [Source:HGNC Symbol;Acc:3620]	Alignment (protein) Alignment (cDNA)	1:161,592,986-161,601,753:-1	97.00 %	90.00 %
Genes (homologues) that have evolved by duplication.Paralogues	Last common ancestor with Marsupials (Marsupialia)Marsupials and Placental mammals (Theria)	ENSG00000143226 FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32) [Source:HGNC Symbol;Acc:3616]	Alignment (protein) Alignment (cDNA)	1:161,475,220-161,493,803:1	33.00 %	37.00 %
Genes (homologues) that have evolved by duplication.Paralogues	Last common ancestor with Marsupials (Marsupialia)Marsupials and Placental mammals (Theria)	ENSG00000072694 FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32) [Source:HGNC Symbol;Acc:3618]	Alignment (protein) Alignment (cDNA)	1:161,551,101-161,648,444:1	33.00 %	35.00 %
Genes (homologues) that have evolved by duplication.Paralogues	Last common ancestor with Marsupials (Marsupialia)Marsupials and Placental mammals (Theria)	ENSG00000150337 FCGR1A Fc fragment of IgG, high affinity Ia, receptor (CD64) [Source:HGNC Symbol;Acc:3613]	Alignment (protein) Alignment (cDNA)	1:149,754,227-149,764,074:1	25.00 %	32.00 %
Genes (homologues) that have evolved by duplication.Paralogues	Last common ancestor with Marsupials (Marsupialia)Marsupials and Placental mammals (Theria)	ENSG00000198019 FCGR1B Fc fragment of IgG, high affinity Ib, receptor (CD64) [Source:HGNC Symbol;Acc:3614]	Alignment (protein) Alignment (cDNA)	1:120,926,979-120,935,937:-1	33.00 %	31.00 %
Genes (homologues) that have evolved by duplication.Paralogues	Last common ancestor with Platypus (Ornithorhynchus anatinus)Mammals (Mammalia)	ENSG00000179639 FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide [Source:HGNC Symbol;Acc:3609]	Alignment (protein) Alignment (cDNA)	1:159,259,504-159,278,014:1	36.00 %	32.00 %
Genes (homologues) that have evolved by duplication.Paralogues	Last common ancestor with Platypus (Ornithorhynchus anatinus)Mammals (Mammalia)	ENSG00000162746 FCRLB Fc receptor-like B [Source:HGNC Symbol;Acc:26431]	Alignment (protein) Alignment (cDNA)	1:161,691,353-161,697,933:1	16.00 %	23.00 %

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