Summary
- Splice variants
- Transcript comparison
- Gene alleles
Sequence
- Secondary Structure
Comparative Genomics
Ontologies
Phenotypes
Genetic Variation
Gene expression
Pathway
Molecular interactions
Regulation
External references
Supporting evidence
ID History
- Gene history

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Gene: BCL2L1 ENSG00000171552

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Description

BCL2-like 1 [Source:HGNC Symbol;Acc:992]

Gene Synonyms

BCL-XL/S, BCL2L, BCLX, BCLXL, BCLXS, Bcl-X, PPP1R52, bcl-xL, bcl-xS

Location

Chromosome 20: 30,252,255-30,311,792 reverse strand.

GRCh37:CM000682.1

About this gene

This gene has 10 transcripts (splice variants) and 3 paralogues.

Transcripts

Show transcript tableHide transcript table

Transcript ID	Name	bp	Protein	Biotype	CCDS	UniProt Match	RefSeq	Flags
ENST00000307677.4	BCL2L1-004	2610	233aa	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS13189	Q07817 Q5QP56 Q5QP59 Q5TE64 Q9H1R6	NM_138578.1	A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000420653.1	BCL2L1-201	2588	233aa	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS13189	Q07817 Q5QP56 Q5QP59 Q5TE64 Q9H1R6	-	A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000376062.2	BCL2L1-001	2578	233aa	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS13189	Q07817 Q5QP56 Q5QP59 Q5TE64 Q9H1R6	-	A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000376055.4	BCL2L1-002	2383	170aa	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS13188	Q07817 Q5QP59 Q5TE63	NM_001191.2	A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000422920.1	BCL2L1-008	1157	188aa	Gene/transcipt that contains an open reading frame (ORF).Protein coding		Q5QP56 Q5QP59 Q9H1R6	-	3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete,
ENST00000456404.1	BCL2L1-007	914	188aa	Gene/transcipt that contains an open reading frame (ORF).Protein coding		Q5QP56 Q5QP59 Q9H1R6	-	3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete,
ENST00000450273.1	BCL2L1-003	894	205aa	Gene/transcipt that contains an open reading frame (ORF).Protein coding		Q5QP56 Q5QP59 Q5TE64 Q9H1R6	-	3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete,
ENST00000420488.1	BCL2L1-006	820	188aa	Gene/transcipt that contains an open reading frame (ORF).Protein coding		Q5QP56 Q5QP59 Q9H1R6	-	3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete,
ENST00000439267.1	BCL2L1-005	781	181aa	Gene/transcipt that contains an open reading frame (ORF).Protein coding		Q5QP56 Q5QP59	-	3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete,
ENST00000434194.1	BCL2L1-009	381	48aa	Gene/transcipt that contains an open reading frame (ORF).Protein coding		Q5QP59	-	3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete,

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Paralogues

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Download paralogues

Type	Ancestral taxonomy	Ensembl identifier & gene name	Compare	Location	Percentage of the paralogous sequence matching the query sequenceTarget %id	Percentage of the query sequence matching the sequence of the paralogueQuery %id
Genes (homologues) that have evolved by duplication.Paralogues	Last common ancestor with Ray-finned fishes (Neopterygii)Bony vertebrates (Euteleostomi)	ENSG00000129473 BCL2L2 BCL2-like 2 [Source:HGNC Symbol;Acc:995]	Alignment (protein) Alignment (cDNA)	14:23,767,999-23,780,968:1	48.00 %	39.00 %
Genes (homologues) that have evolved by duplication.Paralogues	Last common ancestor with Ray-finned fishes (Neopterygii)Bony vertebrates (Euteleostomi)	ENSG00000030110 BAK1 BCL2-antagonist/killer 1 [Source:HGNC Symbol;Acc:949]	Alignment (protein) Alignment (cDNA)	6:33,540,329-33,548,019:-1	22.00 %	20.00 %
Genes (homologues) that have evolved by duplication.Paralogues	Last common ancestor with Ray-finned fishes (Neopterygii)Bony vertebrates (Euteleostomi)	ENSG00000171791 BCL2 B-cell CLL/lymphoma 2 [Source:HGNC Symbol;Acc:990]	Alignment (protein) Alignment (cDNA)	18:60,790,579-60,987,361:-1	41.00 %	42.00 %

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