Summary
- Splice variants
- Transcript comparison
- Gene alleles
Sequence
- Secondary Structure
Comparative Genomics
Ontologies
Phenotypes
Genetic Variation
Gene expression
Pathway
Molecular interactions
Regulation
External references
Supporting evidence
ID History
- Gene history

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Gene: DDX58 ENSG00000107201

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Description

DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 [Source:HGNC Symbol;Acc:19102]

Gene Synonyms

DKFZp434J1111, FLJ13599, RIG-I, RIGI, RLR-1

Location

Chromosome 9: 32,455,300-32,526,322 reverse strand.

GRCh37:CM000671.1

About this gene

This gene has 5 transcripts (splice variants), 3 paralogues and is associated with 2 phenotypes.

Transcripts

Show transcript tableHide transcript table

Transcript ID	Name	bp	Protein	Biotype	CCDS	UniProt Match	RefSeq	Flags
ENST00000379883.2	DDX58-001	4353	925aa	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS6526	A2A376 O95786	NM_014314.3	A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000379882.1	DDX58-201	4621	880aa	Gene/transcipt that contains an open reading frame (ORF).Protein coding		A2A376 O95786	-	A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000379868.1	DDX58-002	4089	722aa	Gene/transcipt that contains an open reading frame (ORF).Protein coding		A2A376	-	A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000542096.1	DDX58-202	3253	854aa	Gene/transcipt that contains an open reading frame (ORF).Protein coding		A2A376 B3KWW1	-	A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000545044.1	DDX58-203	2122	536aa	Gene/transcipt that contains an open reading frame (ORF).Protein coding		F5H5W6	-	A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,

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Paralogues

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Download paralogues

Type	Ancestral taxonomy	Ensembl identifier & gene name	Compare	Location	Percentage of the paralogous sequence matching the query sequenceTarget %id	Percentage of the query sequence matching the sequence of the paralogueQuery %id
Genes (homologues) that have evolved by duplication.Paralogues	Last common ancestor with Lamprey (Petromyzon marinus)Vertebrates (Vertebrata)	ENSG00000115267 IFIH1 interferon induced with helicase C domain 1 [Source:HGNC Symbol;Acc:18873]	Alignment (protein) Alignment (cDNA)	2:163,123,589-163,175,213:-1	29.00 %	33.00 %
Genes (homologues) that have evolved by duplication.Paralogues	Last common ancestor with Lamprey (Petromyzon marinus)Vertebrates (Vertebrata)	ENSG00000108771 DHX58 DEXH (Asp-Glu-X-His) box polypeptide 58 [Source:HGNC Symbol;Acc:29517]	Alignment (protein) Alignment (cDNA)	17:40,253,422-40,264,751:-1	30.00 %	22.00 %
Genes (homologues) that have evolved by duplication.Paralogues	Last common ancestor with Arthropods and nematodes (Ecdysozoa)Bilateral animals (Bilateria)	ENSG00000100697 DICER1 dicer 1, ribonuclease type III [Source:HGNC Symbol;Acc:17098]	Alignment (protein) Alignment (cDNA)	14:95,552,565-95,624,347:-1	8.00 %	17.00 %

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