Description
protein phosphatase 1, regulatory subunit 12A [Source:HGNC Symbol;Acc:7618]
Gene Synonyms
M130, MBS, MYPT1
Location
Chromosome 12: 80,167,343-80,329,240 reverse strand.
GRCh37:CM000674.1
About this gene
This gene has 22 transcripts (splice variants), 207 orthologues, 3 paralogues and is associated with 2 phenotypes.
Transcripts
| Transcript ID | Name | bp | Protein | Translation ID | Biotype | CCDS | UniProt Match | RefSeq | Flags |
|---|---|---|---|---|---|---|---|---|---|
| ENST00000450142.2 | PPP1R12A-001 | 5721 | 1030aa | ENSP00000389168.2 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS44947 | F8VW28 O14974 | NM_002480.2 | A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, |
| ENST00000261207.5 | PPP1R12A-201 | 5582 | 1030aa | ENSP00000261207.5 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS44947 | F8VW28 O14974 | NM_001143885.1 | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, |
| ENST00000437004.2 | PPP1R12A-002 | 4639 | 995aa | ENSP00000416769.2 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS58260 | F8VW28 O14974 | NM_001244990.1 | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, |
| ENST00000546369.1 | PPP1R12A-005 | 2977 | 943aa | ENSP00000449514.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS44948 | F8VW28 O14974 | NM_001143886.1 | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, |
| ENST00000550107.1 | PPP1R12A-004 | 2925 | 974aa | ENSP00000446855.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS58259 | F8VW28 O14974 | NM_001244992.1 | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, |
| ENST00000547330.1 | PPP1R12A-003 | 2275 | 692aa | ENSP00000446816.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | F8VW28 F8VZN8 | - | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete, | |
| ENST00000553081.1 | PPP1R12A-012 | 1101 | 367aa | ENSP00000447144.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | - | - | 5' and 3' truncations in transcript evidence prevent annotation of the start and the end of the CDS.CDS 5' and 3' incomplete, | |
| ENST00000547131.1 | PPP1R12A-011 | 897 | 299aa | ENSP00000450061.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | H0YIS4 | - | 5' and 3' truncations in transcript evidence prevent annotation of the start and the end of the CDS.CDS 5' and 3' incomplete, | |
| ENST00000550299.1 | PPP1R12A-019 | 683 | 188aa | ENSP00000449666.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | - | - | 5' truncation in transcript evidence prevents annotation of the start of the CDS.CDS 5' incomplete, | |
| ENST00000550510.1 | PPP1R12A-008 | 631 | 210aa | ENSP00000447338.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | F8VW28 H0YHL8 | - | 5' and 3' truncations in transcript evidence prevent annotation of the start and the end of the CDS.CDS 5' and 3' incomplete, | |
| ENST00000548318.1 | PPP1R12A-009 | 582 | 97aa | ENSP00000449843.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | F8VW28 | - | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete, | |
| ENST00000546762.1 | PPP1R12A-015 | 1257 | 234aa | ENSP00000450059.1 | Nonsense mediated decay | - | - | 5' truncation in transcript evidence prevents annotation of the start of the CDS.CDS 5' incomplete, | |
| ENST00000550903.1 | PPP1R12A-014 | 959 | 161aa | ENSP00000449647.1 | Nonsense mediated decay | H0YIL7 | - | 5' truncation in transcript evidence prevents annotation of the start of the CDS.CDS 5' incomplete, | |
| ENST00000548908.1 | PPP1R12A-006 | 3066 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - | |
| ENST00000552892.1 | PPP1R12A-007 | 2277 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - | |
| ENST00000550351.1 | PPP1R12A-020 | 738 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - | |
| ENST00000550369.1 | PPP1R12A-016 | 698 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - | |
| ENST00000547253.1 | PPP1R12A-021 | 676 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - | |
| ENST00000550001.1 | PPP1R12A-017 | 631 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - | |
| ENST00000551781.1 | PPP1R12A-013 | 627 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - | |
| ENST00000551191.1 | PPP1R12A-010 | 602 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - | |
| ENST00000550007.1 | PPP1R12A-018 | 443 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - |