Human (GRCh37.p13)
Description

presenilin 2 (Alzheimer disease 4) [Source:HGNC Symbol;Acc:9509]

Gene Synonyms

AD3L, AD4, CMD1V, PS2, PSNL2, STM2

About this transcript

This transcript has 13 exons, is annotated with 25 domains and features, is associated with 11774 variant alleles and maps to 593 oligo probes.

Transcript IDNamebpProteinTranslation IDBiotypeCCDSUniProt MatchRefSeqFlags
ENST00000366782.1PSEN2-0022465481aaENSP00000355746.1
 
Protein coding
B1AP22 B4DVM3 E5RFW4
E5RG63 E5RHT1 E5RJM5
-GENCODE basic
ENST00000366783.3PSEN2-0012302448aaENSP00000355747.3
 
Protein coding
CCDS1556B4DVM3 E5RFW4 E5RG63
E5RHT1 E5RJM5 P49810
NM_012486.2GENCODE basic
ENST00000340188.4PSEN2-2012201415aaENSP00000339860.4
 
Protein coding
C9J5P7 E5RHT1 E5RJM5
-GENCODE basic
ENST00000391872.2PSEN2-2021972481aaENSP00000375745.2
 
Protein coding
B1AP22 B4DVM3 E5RFW4
E5RG63 E5RHT1 E5RJM5
-GENCODE basic
ENST00000422240.2PSEN2-0071947447aaENSP00000403737.2
 
Protein coding
CCDS44324E5RFW4 E5RHT1 E5RJM5
P49810
-GENCODE basic
ENST00000472139.2PSEN2-0061163304aaENSP00000427806.1
 
Protein coding
E5RFW4 E5RG63 -GENCODE basic
ENST00000460775.1PSEN2-005782144aaENSP00000427912.1
 
Protein coding
E5RFW4 -CDS 3' incomplete
ENST00000524196.1PSEN2-01073421aaENSP00000429036.1
 
Protein coding
E5RJM5 -CDS 3' incomplete
ENST00000495488.1PSEN2-004627129aaENSP00000429682.1
 
Protein coding
E5RHT1 E5RJM5 -CDS 3' incomplete
ENST00000496965.1PSEN2-0031614360aaENSP00000430647.1
 
Nonsense mediated decay
E5RFW4 E5RHT1 E5RJ26
E5RJM5
--
ENST00000471728.1PSEN2-009570No protein-
 
Processed transcript
---
ENST00000487450.1PSEN2-008566No protein-
 
Processed transcript
---
ENST00000521431.1PSEN2-011730No protein-
 
Retained intron
---
Statistics

Exons: 13, Coding exons: 10, Transcript length: 1,947 bps, Translation length: 447 residues

Uniprot

This transcript corresponds to the following Uniprot identifiers: P49810

CCDS

This transcript is a member of the Human CCDS set: CCDS44324

Version

ENST00000422240.2

Type

Protein coding

Annotation Method

Transcript where the Ensembl genebuild transcript and the Havana manual annotation have the same sequence, for every base pair. See article.

Alternative transcripts

This transcript corresponds to the following database identifiers:

Transcript having exact match between ENSEMBL and HAVANA:
OTTHUMT00000091545 (version 2)
GENCODE basic gene

This transcript is a member of the Gencode basic gene set.