Transcript: ENST00000288602.6 BRAF-001

Description

v-raf murine sarcoma viral oncogene homolog B [Source:HGNC Symbol;Acc:1097]

Gene Synonyms

B-RAF1, BRAF1, NS7, RAFB1

Location

About this transcript

This transcript has 18 exons, is annotated with 33 domains and features, is associated with 88295 variant alleles and maps to 647 oligo probes.

Gene

Transcript ID	Name	bp	Protein	Translation ID	Biotype	CCDS	UniProt Match	RefSeq	Flags
ENST00000288602.6	BRAF-001	2480	766aa	ENSP00000288602.6	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS5863	D7PBN4 E5FF37 P15056 Q75MQ8	NM_004333.4	A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000496384.2	BRAF-003	8294	375aa	ENSP00000419060.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding		E5FF37	-	5' truncation in transcript evidence prevents annotation of the start of the CDS.CDS 5' incomplete,
ENST00000497784.1	BRAF-002	2336	194aa	ENSP00000420119.1	Nonsense mediated decay		H7C5K3	-	5' truncation in transcript evidence prevents annotation of the start of the CDS.CDS 5' incomplete,
ENST00000479537.1	BRAF-005	743	102aa	ENSP00000418033.1	Nonsense mediated decay		E5FF37 H7C4S5	-	5' truncation in transcript evidence prevents annotation of the start of the CDS.CDS 5' incomplete,
ENST00000469930.1	BRAF-004	1058	No protein	-	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron		-	-	-

Summary

Statistics

Exons: 18, Coding exons: 18, Transcript length: 2,480 bps, Translation length: 766 residues

Uniprot

This transcript corresponds to the following Uniprot identifiers: P15056

CCDS

This transcript is a member of the Human CCDS set: CCDS5863

Version

ENST00000288602.6

Type

Protein coding

Annotation Method

Transcript where the Ensembl genebuild transcript and the Havana manual annotation have the same sequence, for every base pair. See article.

Alternative transcripts

This transcript corresponds to the following database identifiers:

Transcript having exact match between ENSEMBL and HAVANA:	OTTHUMT00000348886 (version 1)

GENCODE basic gene

This transcript is a member of the Gencode basic gene set.