Transcript: ENST00000453137.1 ALK-002

Description

anaplastic lymphoma receptor tyrosine kinase [Source:HGNC Symbol;Acc:427]

Gene Synonyms

CD246, NBLST3

Location

Chromosome 2: 29,443,736-29,446,260 reverse strand.

About this transcript

This transcript has 4 exons, is annotated with 7 domains and features, is associated with 2658 variant alleles and maps to 107 oligo probes.

Gene

This transcript is a product of gene ENSG00000171094.11 Show transcript tableHide transcript table

Transcript ID	Name	bp	Protein	Translation ID	Biotype	CCDS	UniProt Match	RefSeq	Flags
ENST00000389048.3	ALK-001	6220	1620aa	ENSP00000373700.3	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS33172	Q580I3 Q9UM73	NM_004304.4	A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, The GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).GENCODE basic,
ENST00000431873.1	ALK-201	1353	450aa	ENSP00000414027.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding		E7EPW7	-	The GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).GENCODE basic,
ENST00000453137.1	ALK-002	577	152aa	ENSP00000387488.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding		H7BZ33	-	5' truncation in transcript evidence prevents annotation of the start of the CDS.CDS 5' incomplete,
ENST00000498037.1	ALK-003	560	No protein	-	Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript		-	-	-

Summary

Statistics

Exons: 4, Coding exons: 4, Transcript length: 577 bps, Translation length: 152 residues

Incomplete CDS

5' truncation in transcript evidence prevents annotation of the start of the CDS.CDS 5' incomplete

Version

ENST00000453137.1

Type

Protein coding

Annotation Method

Manual annotation (determined on a case-by-case basis) from the Havana project.

Stop codons

This transcript has a variant, rs1569156, that causes a stop codon to be gained in at least 10% of HapMap or 1000 Genome population(s) CSHL-HAPMAP:HapMap-CEU, CSHL-HAPMAP:HAPMAP-CHD, CSHL-HAPMAP:HAPMAP-ASW, CSHL-HAPMAP:HAPMAP-LWK, CSHL-HAPMAP:HAPMAP-CHB, CSHL-HAPMAP:HAPMAP-MKK, CSHL-HAPMAP:HapMap-HCB, CSHL-HAPMAP:HapMap-YRI, CSHL-HAPMAP:HAPMAP-MEX, CSHL-HAPMAP:HapMap-JPT.

Alternative transcripts

This transcript corresponds to the following database identifiers:

Havana transcript:	OTTHUMT00000324995 (version 1)

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Transcript: ENST00000453137.1 ALK-002

Summary