Transcript: ENST00000528762.1 BRCA2-005

Description

breast cancer 2, early onset [Source:HGNC Symbol;Acc:1101]

Gene Synonyms

BRCC2, BROVCA2, FACD, FAD, FAD1, FANCB, FANCD, FANCD1, GLM3, PNCA2

Location

Chromosome 13: 32,945,108-32,953,632 forward strand.

About this transcript

This transcript has 4 exons, is annotated with 4 domains and features, is associated with 4962 variant alleles and maps to 67 oligo probes.

Gene

This transcript is a product of gene ENSG00000139618.10 Show transcript tableHide transcript table

Transcript ID	Name	bp	Protein	Translation ID	Biotype	CCDS	UniProt Match	RefSeq	Flags
ENST00000544455.1	BRCA2-201	10984	3418aa	ENSP00000439902.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS9344	E9PIQ1 K4JTT2 K4JXT6 K4K7W0 P51587 Q8IU64 Q8IU77 Q8IU82 Q9H4L3	NM_000059.3	A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, The GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).GENCODE basic,
ENST00000380152.3	BRCA2-001	10930	3418aa	ENSP00000369497.3	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS9344	E9PIQ1 K4JTT2 K4JXT6 K4K7W0 P51587 Q8IU64 Q8IU77 Q8IU82 Q9H4L3	-	The GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).GENCODE basic,
ENST00000530893.2	BRCA2-003	2011	481aa	ENSP00000435699.2	Gene/transcipt that contains an open reading frame (ORF).Protein coding		E9PIQ1 Q8IU82	-	3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete,
ENST00000470094.1	BRCA2-002	842	186aa	ENSP00000434898.1	Nonsense mediated decay		-	-	5' truncation in transcript evidence prevents annotation of the start of the CDS.CDS 5' incomplete,
ENST00000528762.1	BRCA2-005	495	64aa	ENSP00000433168.1	Nonsense mediated decay		H0YD86	-	5' truncation in transcript evidence prevents annotation of the start of the CDS.CDS 5' incomplete,
ENST00000533776.1	BRCA2-006	523	No protein	-	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron		-	-	-

Summary

Statistics

Exons: 4, Coding exons: 3, Transcript length: 495 bps, Translation length: 64 residues

Incomplete CDS

5' truncation in transcript evidence prevents annotation of the start of the CDS.CDS 5' incomplete

Version

ENST00000528762.1

Type

Nonsense mediated decay

Annotation Method

Manual annotation (determined on a case-by-case basis) from the Havana project.

Alternative transcripts

This transcript corresponds to the following database identifiers:

Havana transcript:	OTTHUMT00000387478 (version 1)

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Transcript: ENST00000528762.1 BRCA2-005

Summary