Transcript: ENST00000436439.2 HMGCL-007

Description

3-hydroxymethyl-3-methylglutaryl-CoA lyase [Source:HGNC Symbol;Acc:5005]

Gene Synonyms

Location

Chromosome 1: 24,128,377-24,151,918 reverse strand.

About this transcript

This transcript has 7 exons, is annotated with 8 domains and features, is associated with 10108 variant alleles and maps to 380 oligo probes.

Gene

This transcript is a product of gene ENSG00000117305.10 Show transcript tableHide transcript table

Transcript ID	Name	bp	Protein	Translation ID	Biotype	CCDS	UniProt Match	RefSeq	Flags
ENST00000374490.3	HMGCL-002	1600	325aa	ENSP00000363614.3	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS243	B1AK13 P35914	NM_000191.2	A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, The GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).GENCODE basic,
ENST00000374483.4	HMGCL-201	2151	300aa	ENSP00000363607.4	Gene/transcipt that contains an open reading frame (ORF).Protein coding		B1AK13	-	The GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).GENCODE basic,
ENST00000436439.2	HMGCL-007	1354	254aa	ENSP00000389281.2	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS53279	P35914	NM_001166059.1	The GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).GENCODE basic,
ENST00000235958.4	HMGCL-010	1101	182aa	ENSP00000235958.4	Gene/transcipt that contains an open reading frame (ORF).Protein coding		-	-	5' truncation in transcript evidence prevents annotation of the start of the CDS.CDS 5' incomplete,
ENST00000374487.2	HMGCL-001	2151	77aa	ENSP00000363611.2	Nonsense mediated decay		D6REN8	-	-
ENST00000509389.1	HMGCL-008	1379	No protein	-	Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript		-	-	-
ENST00000496907.1	HMGCL-006	858	No protein	-	Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript		-	-	-
ENST00000479458.1	HMGCL-003	594	No protein	-	Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript		-	-	-
ENST00000498698.1	HMGCL-004	463	No protein	-	Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript		-	-	-
ENST00000513148.1	HMGCL-009	2011	No protein	-	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron		-	-	-

Summary

Statistics

Exons: 7, Coding exons: 7, Transcript length: 1,354 bps, Translation length: 254 residues

Uniprot

This transcript corresponds to the following Uniprot identifiers: P35914

CCDS

This transcript is a member of the Human CCDS set: CCDS53279

Version

ENST00000436439.2

Type

Protein coding

Annotation Method

Transcript where the Ensembl genebuild transcript and the Havana manual annotation have the same sequence, for every base pair. See article.

Alternative transcripts

This transcript corresponds to the following database identifiers:

Transcript having exact match between ENSEMBL and HAVANA:	OTTHUMT00000372570 (version 1)

GENCODE basic gene

This transcript is a member of the Gencode basic gene set.

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Transcript: ENST00000436439.2 HMGCL-007

Summary