Transcript: ENST00000222219.3 DNASE2-001

Description

deoxyribonuclease II, lysosomal [Source:HGNC Symbol;Acc:2960]

Gene Synonyms

DNASE2A, DNL, DNL2

Location

Chromosome 19: 12,986,025-12,992,282 reverse strand.

About this transcript

This transcript has 6 exons, is annotated with 6 domains and features, is associated with 3047 variant alleles and maps to 516 oligo probes.

Gene

This transcript is a product of gene ENSG00000105612.4 Show transcript tableHide transcript table

Transcript ID	Name	bp	Protein	Translation ID	Biotype	CCDS	UniProt Match	RefSeq	Flags
ENST00000222219.3	DNASE2-001	1955	360aa	ENSP00000222219.2	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS12284	O00115	NM_001375.2	A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, The GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).GENCODE basic,
ENST00000538460.1	DNASE2-201	1037	305aa	ENSP00000445988.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding		B7Z4K6 K7ENE5	-	The GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).GENCODE basic,
ENST00000592506.1	DNASE2-002	745	218aa	ENSP00000466912.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding		K7ENE5	-	3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete,
ENST00000588777.1	DNASE2-004	727	No protein	-	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron		-	-	-
ENST00000586547.1	DNASE2-003	707	No protein	-	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron		-	-	-

Summary

Statistics

Exons: 6, Coding exons: 6, Transcript length: 1,955 bps, Translation length: 360 residues

Uniprot

This transcript corresponds to the following Uniprot identifiers: O00115

CCDS

This transcript is a member of the Human CCDS set: CCDS12284

Version

ENST00000222219.3

Type

Protein coding

Annotation Method

Transcript where the Ensembl genebuild transcript and the Havana manual annotation have the same sequence, for every base pair. See article.

Alternative transcripts

This transcript corresponds to the following database identifiers:

Transcript having exact match between ENSEMBL and HAVANA:	OTTHUMT00000451790 (version 1)

GENCODE basic gene

This transcript is a member of the Gencode basic gene set.

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Transcript: ENST00000222219.3 DNASE2-001

Summary