Gene: CHEK2 ENSG00000183765

Description

checkpoint kinase 2 [Source:HGNC Symbol;Acc:16627]

Gene Synonyms

CDS1, CHK2, HuCds1, LFS2, PP1425, RAD53, bA444G7, hCds1

Location

Chromosome 22: 29,083,731-29,138,410 reverse strand.

GRCh37:CM000684.1

About this gene

This gene has 27 transcripts (splice variants) and is associated with 82 phenotypes.

Transcripts

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Transcript ID	Name	bp	Protein	Translation ID	Biotype	CCDS	UniProt Match	RefSeq	Flags
ENST00000382580.2	CHEK2-003	1971	586aa	ENSP00000372023.2	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS33629	B7ZBF2 O96017	NM_001005735.1	A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000544772.1	CHEK2-205	2560	322aa	ENSP00000442458.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS58798	B7ZBF2 O96017	NM_001257387.1	A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000405598.1	CHEK2-005	1959	543aa	ENSP00000386087.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS13843	B7ZBF2 O96017	-	A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000328354.6	CHEK2-002	1867	543aa	ENSP00000329178.6	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS13843	B7ZBF2 O96017	NM_007194.3	A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000382566.1	CHEK2-203	1796	289aa	ENSP00000372007.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding		O96017	-	A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000404276.1	CHEK2-006	1785	543aa	ENSP00000385747.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS13843	B7ZBF2 O96017	-	A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000348295.3	CHEK2-201	1771	514aa	ENSP00000329012.5	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS13844	O96017	NM_145862.2	A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000382578.1	CHEK2-204	1585	452aa	ENSP00000372021.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding		B7ZBF2 O96017	-	A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000402731.1	CHEK2-022	1545	514aa	ENSP00000384835.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS13844	O96017	-	A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000403642.1	CHEK2-021	1359	452aa	ENSP00000384919.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding		B7ZBF2 O96017	-	A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000434810.1	CHEK2-018	984	276aa	ENSP00000416721.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding		-	-	5' truncation in transcript evidence prevents annotation of the start of the CDS.CDS 5' incomplete,
ENST00000439200.1	CHEK2-013	906	295aa	ENSP00000408065.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding		B7ZBF7	-	3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete,
ENST00000447421.1	CHEK2-010	903	299aa	ENSP00000397478.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding		B7ZBF6	-	3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete,
ENST00000425190.2	CHEK2-011	752	121aa	ENSP00000390244.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding		B7ZBF2	-	3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete,
ENST00000382565.1	CHEK2-202	718	163aa	ENSP00000372006.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding		C9JFD7	-	A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000398017.2	CHEK2-012	713	172aa	ENSP00000381099.2	Gene/transcipt that contains an open reading frame (ORF).Protein coding		B7ZBF8	-	3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete,
ENST00000456369.1	CHEK2-019	588	144aa	ENSP00000394430.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding		-	-	5' truncation in transcript evidence prevents annotation of the start of the CDS.CDS 5' incomplete,
ENST00000416671.1	CHEK2-001	2560	207aa	ENSP00000402225.1	Nonsense mediated decay		E7EPP1	-	-
ENST00000433728.1	CHEK2-023	1580	289aa	ENSP00000404400.1	Nonsense mediated decay		O96017	-	-
ENST00000417588.1	CHEK2-009	1551	203aa	ENSP00000412901.1	Nonsense mediated decay		H7C0V7 O96017	-	-
ENST00000448511.1	CHEK2-008	1532	165aa	ENSP00000404567.1	Nonsense mediated decay		O96017	-	-
ENST00000433028.2	CHEK2-004	1349	161aa	ENSP00000403659.1	Nonsense mediated decay		F8WCV2	-	-
ENST00000454252.1	CHEK2-014	722	45aa	ENSP00000387451.1	Nonsense mediated decay		H7BZ30	-	5' truncation in transcript evidence prevents annotation of the start of the CDS.CDS 5' incomplete,
ENST00000439346.1	CHEK2-015	553	57aa	ENSP00000396903.1	Nonsense mediated decay		H7C0V7	-	5' truncation in transcript evidence prevents annotation of the start of the CDS.CDS 5' incomplete,
ENST00000464581.1	CHEK2-017	425	No protein	-	Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript		-	-	-
ENST00000491919.1	CHEK2-016	609	No protein	-	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron		-	-	-
ENST00000472807.1	CHEK2-020	514	No protein	-	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron		-	-	-

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Gene: CHEK2 ENSG00000183765

Summary