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Summary
- Splice variants
- Transcript comparison
- Gene alleles
Sequence
- Secondary Structure
Comparative Genomics
- Paralogues
- Genomic alignments
- Gene tree
- Gene gain/loss tree
- Orthologues
Ontologies
Phenotypes
Genetic Variation
Gene expression
Pathway
Molecular interactions
Regulation
External references
Supporting evidence
ID History
- Gene history

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Gene: CHEK1 ENSG00000149554

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Description

checkpoint kinase 1 [Source:HGNC Symbol;Acc:1925]

Gene Synonyms

CHK1

Location

Chromosome 11: 125,495,036-125,546,150 forward strand.

GRCh37:CM000673.1

About this gene

This gene has 19 transcripts (splice variants).

Transcripts

Show transcript tableHide transcript table

Transcript ID	Name	bp	Protein	Translation ID	Biotype	CCDS	UniProt Match	RefSeq	Flags
ENST00000534070.1	CHEK1-004	3502	476aa	ENSP00000435371.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS8459	E9PJI4 E9PKQ3 E9PM65 E9PQW7 E9PRU7 O14757 Q6W8P8	NM_001274.5	A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000438015.1	CHEK1-201	2748	476aa	ENSP00000388648.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS8459	E9PJI4 E9PKQ3 E9PM65 E9PQW7 E9PRU7 O14757 Q6W8P8	NM_001244846.1	A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000428830.2	CHEK1-002	1845	476aa	ENSP00000412504.2	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS8459	E9PJI4 E9PKQ3 E9PM65 E9PQW7 E9PRU7 O14757 Q6W8P8	NM_001114121.2	A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000524737.1	CHEK1-007	1799	476aa	ENSP00000432890.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS8459	E9PJI4 E9PKQ3 E9PM65 E9PQW7 E9PRU7 O14757 Q6W8P8	-	A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000278916.3	CHEK1-006	1713	432aa	ENSP00000278916.3	Gene/transcipt that contains an open reading frame (ORF).Protein coding		E9PJI4 E9PKQ3 E9PM65 E9PQW7 E9PRU7 J3KN87 Q6W8P8	-	A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000427383.2	CHEK1-001	1670	492aa	ENSP00000391090.2	Gene/transcipt that contains an open reading frame (ORF).Protein coding		E7EPP6	-	A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000544373.1	CHEK1-202	1568	442aa	ENSP00000442317.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS58191	E9PJI4 E9PKQ3 E9PM65 E9PQW7 E9PRU7 O14757 Q6W8P8	-	A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000525396.1	CHEK1-018	769	133aa	ENSP00000434141.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding		E9PM65 E9PQW7 E9PRU7 Q6W8P8	-	3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete,
ENST00000527013.1	CHEK1-011	661	204aa	ENSP00000431525.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding		E9PJI4 E9PKQ3 E9PM65 E9PQW7 E9PRU7 Q6W8P8	-	3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete,
ENST00000532669.1	CHEK1-013	599	192aa	ENSP00000434646.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding		E9PPA5	-	3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete,
ENST00000534685.1	CHEK1-008	583	127aa	ENSP00000432470.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding		E9PM65 E9PQW7 Q6W8P8	-	3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete,
ENST00000526937.1	CHEK1-010	562	170aa	ENSP00000431815.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding		E9PJI4 E9PM65 E9PQW7 E9PRU7 Q6W8P8	-	3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete,
ENST00000533778.2	CHEK1-009	561	42aa	ENSP00000433103.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding		E9PM65 Q6W8P8	-	3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete,
ENST00000532449.1	CHEK1-005	1653	No protein	-	Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript		-	-	-
ENST00000528761.1	CHEK1-019	761	No protein	-	Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript		-	-	-
ENST00000498122.3	CHEK1-016	755	No protein	-	Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript		-	-	-
ENST00000531607.1	CHEK1-012	463	No protein	-	Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript		-	-	-
ENST00000528276.1	CHEK1-015	1814	No protein	-	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron		-	-	-
ENST00000531062.1	CHEK1-014	772	No protein	-	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron		-	-	-

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Summary

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