Description
tropomyosin 1 (alpha) [Source:HGNC Symbol;Acc:12010]
Gene Synonyms
C15orf13, CMD1Y, CMH3, HTM-alpha, LVNC9, TMSA
Location
Chromosome 15: 63,334,831-63,364,114 forward strand.
GRCh37:CM000677.1
About this gene
This gene has 32 transcripts (splice variants), 3 paralogues and is associated with 6 phenotypes.
Transcripts
| Transcript ID | Name | bp | Protein | Translation ID | Biotype | CCDS | UniProt Match | RefSeq | Flags |
|---|---|---|---|---|---|---|---|---|---|
| ENST00000358278.3 | TPM1-018 | 1717 | 284aa | ENSP00000351022.3 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS32263 | D9YZV5 H0YL42 P09493 | NM_001018006.1 | A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, |
| ENST00000357980.4 | TPM1-008 | 1800 | 326aa | ENSP00000350667.4 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | Q6ZN40 | - | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, | |
| ENST00000267996.7 | TPM1-005 | 1670 | 284aa | ENSP00000267996.7 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS32262 | P09493 | NM_001018007.1 | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, |
| ENST00000559397.1 | TPM1-010 | 1655 | 284aa | ENSP00000452879.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS58368 | H0YL42 P09493 | NM_001018020.1 | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, |
| ENST00000334895.5 | TPM1-011 | 1637 | 245aa | ENSP00000334624.4 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS32264 | D9YZV7 P09493 Q07413 | NM_001018008.1 | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, |
| ENST00000404484.4 | TPM1-012 | 1568 | 248aa | ENSP00000384315.4 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | H0YL42 H7BYY1 Q07413 | - | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, | |
| ENST00000288398.6 | TPM1-001 | 1295 | 284aa | ENSP00000288398.6 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS10181 | H0YL42 P09493 | NM_000366.5 | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, |
| ENST00000403994.3 | TPM1-002 | 1049 | 284aa | ENSP00000385107.3 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS45273 | D9YZV4 P09493 | NM_001018005.1 | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, |
| ENST00000560970.1 | TPM1-003 | 1039 | 265aa | ENSP00000453062.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | - | - | 5' truncation in transcript evidence prevents annotation of the start of the CDS.CDS 5' incomplete, | |
| ENST00000559556.1 | TPM1-028 | 977 | 284aa | ENSP00000453941.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS58369 | P09493 | NM_001018004.1 | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, |
| ENST00000560959.1 | TPM1-014 | 925 | 275aa | ENSP00000453724.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | B7Z596 H0YL42 Q07413 | - | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, | |
| ENST00000559281.1 | TPM1-015 | 851 | 248aa | ENSP00000452658.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | H0YK48 Q07413 | - | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, | |
| ENST00000558910.1 | TPM1-023 | 782 | 33aa | ENSP00000452830.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | - | - | 5' truncation in transcript evidence prevents annotation of the start of the CDS.CDS 5' incomplete, | |
| ENST00000317516.7 | TPM1-016 | 738 | 245aa | ENSP00000322577.7 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | F5H7S3 H0YL42 Q07413 | - | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, | |
| ENST00000561266.1 | TPM1-027 | 671 | 223aa | ENSP00000453955.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | - | - | 5' truncation in transcript evidence prevents annotation of the start of the CDS.CDS 5' incomplete, | |
| ENST00000560615.1 | TPM1-022 | 570 | 108aa | ENSP00000453050.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | H0YL42 | - | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete, | |
| ENST00000560445.1 | TPM1-019 | 485 | 70aa | ENSP00000452999.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | H0YKZ6 | - | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, | |
| ENST00000560679.1 | TPM1-024 | 292 | 8aa | ENSP00000453136.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | - | - | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete, | |
| ENST00000558264.1 | TPM1-017 | 2687 | 92aa | ENSP00000452624.1 | Nonsense mediated decay | H0YK20 | - | - | |
| ENST00000558347.1 | TPM1-009 | 1525 | 157aa | ENSP00000452887.1 | Nonsense mediated decay | H0YKP3 | - | - | |
| ENST00000558544.1 | TPM1-013 | 1399 | 49aa | ENSP00000453817.1 | Nonsense mediated decay | H0YN06 Q07413 | - | - | |
| ENST00000561395.1 | TPM1-033 | 673 | 68aa | ENSP00000453092.1 | Nonsense mediated decay | H0YL80 | - | 5' truncation in transcript evidence prevents annotation of the start of the CDS.CDS 5' incomplete, | |
| ENST00000561425.1 | TPM1-020 | 582 | 40aa | ENSP00000453324.1 | Nonsense mediated decay | H0YLS7 | - | - | |
| ENST00000559831.1 | TPM1-029 | 573 | 142aa | ENSP00000452977.1 | Nonsense mediated decay | H0YK20 H0YKX5 | - | 5' truncation in transcript evidence prevents annotation of the start of the CDS.CDS 5' incomplete, | |
| ENST00000560975.1 | TPM1-007 | 2855 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - | |
| ENST00000558314.1 | TPM1-006 | 1031 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - | |
| ENST00000561242.1 | TPM1-032 | 673 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - | |
| ENST00000558400.1 | TPM1-030 | 658 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - | |
| ENST00000558868.1 | TPM1-021 | 653 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - | |
| ENST00000560131.1 | TPM1-026 | 537 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - | |
| ENST00000558072.1 | TPM1-025 | 525 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - | |
| ENST00000559108.1 | TPM1-031 | 437 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - |
