Description
adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2 [Source:HGNC Symbol;Acc:18242]
Gene Synonyms
DIP13B, FLJ10659
Location
Chromosome 12: 105,567,074-105,630,016 reverse strand.
GRCh37:CM000674.1
About this gene
This gene has 16 transcripts (splice variants), 203 orthologues and 28 paralogues.
Transcripts
| Transcript ID | Name | bp | Protein | Translation ID | Biotype | CCDS | UniProt Match | RefSeq | Flags |
|---|---|---|---|---|---|---|---|---|---|
| ENST00000551662.1 | APPL2-004 | 2190 | 670aa | ENSP00000446917.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS58276 | F8W124 Q8NEU8 | - | A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, |
| ENST00000258530.3 | APPL2-001 | 3239 | 664aa | ENSP00000258530.3 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS9101 | F8W124 Q8NEU8 | NM_018171.3 | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, |
| ENST00000539978.2 | APPL2-002 | 2680 | 621aa | ENSP00000444472.2 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS58275 | F8W124 Q8NEU8 | NM_001251905.1 | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, |
| ENST00000546731.1 | APPL2-016 | 684 | 107aa | ENSP00000447828.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | F8VS86 | - | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, | |
| ENST00000553109.1 | APPL2-013 | 564 | 188aa | ENSP00000446510.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | H0YH86 | - | 5' and 3' truncations in transcript evidence prevent annotation of the start and the end of the CDS.CDS 5' and 3' incomplete, | |
| ENST00000553097.1 | APPL2-006 | 514 | 144aa | ENSP00000449767.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | F8VWV2 | - | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete, | |
| ENST00000549056.1 | APPL2-007 | 493 | 61aa | ENSP00000447520.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | F8W124 | - | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete, | |
| ENST00000547439.1 | APPL2-005 | 3196 | 235aa | ENSP00000449410.1 | Nonsense mediated decay | F8VXB0 F8W124 | - | - | |
| ENST00000549974.1 | APPL2-008 | 547 | 39aa | ENSP00000448569.1 | Nonsense mediated decay | F8VR68 | - | - | |
| ENST00000549573.1 | APPL2-011 | 555 | No protein | - | Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript | - | - | - | |
| ENST00000552945.1 | APPL2-012 | 372 | No protein | - | Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript | - | - | - | |
| ENST00000547809.1 | APPL2-003 | 1797 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - | |
| ENST00000547790.1 | APPL2-015 | 851 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - | |
| ENST00000546768.1 | APPL2-009 | 637 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - | |
| ENST00000550648.1 | APPL2-010 | 529 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - | |
| ENST00000548425.1 | APPL2-014 | 428 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - |
