Description
transforming growth factor, beta receptor 1 [Source:HGNC Symbol;Acc:11772]
Gene Synonyms
AAT5, ACVRLK4, ALK-5, ALK5, LDS1A, LDS2A, MSSE, SKR4, TGFR-1
Location
Chromosome 9: 101,866,320-101,916,474 forward strand.
GRCh37:CM000671.1
About this gene
This gene has 10 transcripts (splice variants), 227 orthologues, 11 paralogues and is associated with 10 phenotypes.
Transcripts
| Transcript ID | Name | bp | Protein | Translation ID | Biotype | CCDS | UniProt Match | RefSeq | Flags |
|---|---|---|---|---|---|---|---|---|---|
| ENST00000374994.4 | TGFBR1-001 | 6516 | 503aa | ENSP00000364133.4 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS6738 | B4DY26 F8VVC4 P36897 Q5T7S2 | NM_004612.2 | A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, |
| ENST00000552516.1 | TGFBR1-004 | 5933 | 507aa | ENSP00000447297.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | F8VRH6 F8W0K6 P36897 | - | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, | |
| ENST00000374990.2 | TGFBR1-003 | 5720 | 426aa | ENSP00000364129.2 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS47998 | F8VXZ5 P36897 | NM_001130916.1 | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, |
| ENST00000550253.1 | TGFBR1-007 | 1538 | 434aa | ENSP00000450052.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | B4DY26 F8VVC4 | - | A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, | |
| ENST00000549021.1 | TGFBR1-010 | 680 | 114aa | ENSP00000449028.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | F8VXZ5 | - | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete, | |
| ENST00000548365.1 | TGFBR1-011 | 582 | 114aa | ENSP00000448518.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | F8VRH6 | - | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete, | |
| ENST00000546584.1 | TGFBR1-012 | 565 | 188aa | ENSP00000447707.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | F8VVC4 H0YHS4 | - | 5' and 3' truncations in transcript evidence prevent annotation of the start and the end of the CDS.CDS 5' and 3' incomplete, | |
| ENST00000547314.1 | TGFBR1-008 | 533 | 118aa | ENSP00000449934.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | F8VVC4 | - | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete, | |
| ENST00000552573.2 | TGFBR1-009 | 526 | 126aa | ENSP00000447182.2 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | F8VRH6 F8W0K6 | - | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete, | |
| ENST00000549766.1 | TGFBR1-005 | 1678 | 383aa | ENSP00000446685.1 | Nonsense mediated decay | F8VRH6 F8W0K6 F8W1R9 | - | - |
