Gene: APP ENSG00000142192

Description

amyloid beta (A4) precursor protein [Source:HGNC Symbol;Acc:620]

Gene Synonyms

A4, AAA, ABETA, ABPP, AD1, APPI, CTFgamma, CVAP, PN-II, PN2

Location

Chromosome 21: 27,252,861-27,543,446 reverse strand.

GRCh37:CM000683.1

About this gene

This gene has 19 transcripts (splice variants), 2 paralogues and is associated with 9 phenotypes.

Transcripts

Show transcript tableHide transcript table

Transcript ID	Name	bp	Protein	Translation ID	Biotype	CCDS	UniProt Match	RefSeq	Flags
ENST00000358918.3	APP-201	3578	752aa	ENSP00000351796.3	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS56213	H7C104 L7XCZ9 L7XE61 P05067	NM_001204302.1	The GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).GENCODE basic,
ENST00000357903.3	APP-001	3543	751aa	ENSP00000350578.3	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS33523	B7Z313 L7XCZ9 L7XE61 P05067	NM_201413.2	The GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).GENCODE basic,
ENST00000346798.3	APP-004	3467	770aa	ENSP00000284981.4	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS13576	B7Z313 L7XCZ9 L7XE61 P05067	NM_000484.3	The GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).GENCODE basic,
ENST00000359726.3	APP-202	3464	714aa	ENSP00000352760.3	Gene/transcipt that contains an open reading frame (ORF).Protein coding		B7Z313 L7XCZ9 L7XE61 P05067	-	The GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).GENCODE basic,
ENST00000348990.5	APP-003	3355	695aa	ENSP00000345463.5	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS13577	B7Z313 E9PEV0 L7XCZ9 L7XE61 P05067	NM_201414.2	The GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).GENCODE basic,
ENST00000354192.3	APP-002	3167	639aa	ENSP00000346129.3	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS46638	B7Z313 L7XCZ9 L7XE61 P05067	NM_001136129.2	The GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).GENCODE basic,
ENST00000440126.3	APP-016	2846	746aa	ENSP00000387483.2	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS56212	B7Z313 L7XCZ9 L7XE61 P05067	NM_001136016.3	The GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).GENCODE basic,
ENST00000448388.2	APP-203	2518	660aa	ENSP00000388538.2	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS56211	B7Z313 E9PEV0 L7XCZ9 L7XE61	NM_001136131.2	The GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).GENCODE basic,
ENST00000439274.2	APP-015	2517	714aa	ENSP00000398879.2	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS46639	B7Z313 E9PG40 L7XCZ9 L7XE61	NM_001136130.2	The GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).GENCODE basic,
ENST00000448850.1	APP-005	1846	485aa	ENSP00000396923.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding		-	-	5' truncation in transcript evidence prevents annotation of the start of the CDS.CDS 5' incomplete,
ENST00000456209.2	APP-011	842	280aa	ENSP00000397795.2	Gene/transcipt that contains an open reading frame (ORF).Protein coding		H7C104 L7XE61	-	5' and 3' truncations in transcript evidence prevent annotation of the start and the end of the CDS.CDS 5' and 3' incomplete,
ENST00000415997.1	APP-010	541	181aa	ENSP00000406539.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding		-	-	5' and 3' truncations in transcript evidence prevent annotation of the start and the end of the CDS.CDS 5' and 3' incomplete,
ENST00000474136.1	APP-013	1309	No protein	-	Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript		-	-	-
ENST00000491395.1	APP-009	619	No protein	-	Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript		-	-	-
ENST00000463070.1	APP-008	582	No protein	-	Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript		-	-	-
ENST00000466453.1	APP-006	374	No protein	-	Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript		-	-	-
ENST00000548570.1	APP-014	361	No protein	-	Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript		-	-	-
ENST00000464867.1	APP-012	816	No protein	-	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron		-	-	-
ENST00000462267.1	APP-007	667	No protein	-	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron		-	-	-

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Gene: APP ENSG00000142192

Summary