Description
pleckstrin homology domain containing, family M (with RUN domain) member 1 [Source:HGNC Symbol;Acc:29017]
Gene Synonyms
AP162, B2, KIAA0356, OPTB6
Location
Chromosome 17: 43,513,266-43,568,115 reverse strand.
GRCh37:CM000679.1
About this gene
This gene has 19 transcripts (splice variants), 4 paralogues and is associated with 2 phenotypes.
Transcripts
| Transcript ID | Name | bp | Protein | Translation ID | Biotype | CCDS | UniProt Match | RefSeq | Flags |
|---|---|---|---|---|---|---|---|---|---|
| ENST00000430334.3 | PLEKHM1-001 | 5263 | 1056aa | ENSP00000389913.3 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS32671 | J3KRL8 K7EII8 Q9Y4G2 | NM_014798.2 | A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, The GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).GENCODE basic, |
| ENST00000421073.2 | PLEKHM1-201 | 4995 | 967aa | ENSP00000414352.2 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | F8W648 J3KRL8 | - | The GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).GENCODE basic, | |
| ENST00000591580.1 | PLEKHM1-017 | 650 | 113aa | ENSP00000467695.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | - | - | 5' truncation in transcript evidence prevents annotation of the start of the CDS.CDS 5' incomplete, | |
| ENST00000584420.1 | PLEKHM1-009 | 603 | 140aa | ENSP00000462065.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | J3KRL8 | - | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete, | |
| ENST00000589780.1 | PLEKHM1-015 | 587 | 152aa | ENSP00000467356.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | K7EPF2 | - | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete, | |
| ENST00000579197.1 | PLEKHM1-003 | 4995 | 63aa | ENSP00000462282.1 | Nonsense mediated decay | J3KS30 | - | - | |
| ENST00000581448.1 | PLEKHM1-002 | 3292 | 335aa | ENSP00000462160.1 | Nonsense mediated decay | J3KRL8 J3KRU0 K7EII8 | - | - | |
| ENST00000446609.2 | PLEKHM1-004 | 2825 | 63aa | ENSP00000394344.2 | Nonsense mediated decay | J3KS30 | - | - | |
| ENST00000586084.1 | PLEKHM1-016 | 553 | 99aa | ENSP00000464766.1 | Nonsense mediated decay | K7EII8 | - | - | |
| ENST00000590991.1 | PLEKHM1-018 | 327 | 45aa | ENSP00000466589.1 | Nonsense mediated decay | K7EMP2 | - | 5' truncation in transcript evidence prevents annotation of the start of the CDS.CDS 5' incomplete, | |
| ENST00000580404.1 | PLEKHM1-008 | 2628 | No protein | - | Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript | - | - | - | |
| ENST00000580205.1 | PLEKHM1-006 | 2385 | No protein | - | Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript | - | - | - | |
| ENST00000582119.1 | PLEKHM1-010 | 572 | No protein | - | Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript | - | - | - | |
| ENST00000586562.1 | PLEKHM1-014 | 550 | No protein | - | Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript | - | - | - | |
| ENST00000579131.1 | PLEKHM1-012 | 499 | No protein | - | Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript | - | - | - | |
| ENST00000583150.1 | PLEKHM1-013 | 479 | No protein | - | Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript | - | - | - | |
| ENST00000582035.1 | PLEKHM1-007 | 1834 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - | |
| ENST00000581932.2 | PLEKHM1-005 | 1163 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - | |
| ENST00000585506.1 | PLEKHM1-019 | 332 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - |
