Gene: PTPN11 ENSG00000179295

Description

protein tyrosine phosphatase, non-receptor type 11 [Source:HGNC Symbol;Acc:9644]

Gene Synonyms

BPTP3, CFC, NS1, PTP-1D, PTP2C, SH-PTP2, SH-PTP3, SHP-2, SHP2, SHPTP2

Location

GRCh37:CM000674.1

About this gene

This gene has 4 transcripts (splice variants), 13 paralogues and is associated with 89 phenotypes.

Transcripts

Transcript ID	Name	bp	Protein	Translation ID	Biotype	CCDS	UniProt Match	RefSeq	Flags
ENST00000351677.2	PTPN11-001	6101	593aa	ENSP00000340944.2	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS9163	B3GUD3 B3GUD4 Q06124	NM_002834.3	A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, The GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).GENCODE basic,
ENST00000392597.1	PTPN11-002	1876	460aa	ENSP00000376376.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS58280	B3GUD3 B3GUD4 Q06124	NM_080601.1	The GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).GENCODE basic,
ENST00000530818.1	PTPN11-004	486	108aa	ENSP00000437013.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding		-	-	5' truncation in transcript evidence prevents annotation of the start of the CDS.CDS 5' incomplete,
ENST00000531326.1	PTPN11-003	573	No protein	-	Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript		-	-	-

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