Gene: HTRA1 ENSG00000166033

Description

HtrA serine peptidase 1 [Source:HGNC Symbol;Acc:9476]

Gene Synonyms

ARMD7, CARASIL, HTRA, HtrA, IGFBP5-protease, L56, ORF480, PRSS11

Location

GRCh37:CM000672.1

About this gene

This gene has 2 transcripts (splice variants), 3 paralogues and is associated with 7 phenotypes.

Transcripts

Transcript ID	Name	bp	Protein	Translation ID	Biotype	CCDS	UniProt Match	RefSeq	Flags
ENST00000368984.3	HTRA1-001	2120	480aa	ENSP00000357980.3	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS7630	A8K224 H0Y7G9 Q92743	NM_002775.4	A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, The GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).GENCODE basic,
ENST00000420892.1	HTRA1-002	1214	221aa	ENSP00000412676.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding		A8K224 H0Y7G9	-	5' truncation in transcript evidence prevents annotation of the start of the CDS.CDS 5' incomplete,

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