Gene: BRAF ENSG00000157764

Description

v-raf murine sarcoma viral oncogene homolog B [Source:HGNC Symbol;Acc:1097]

Gene Synonyms

B-RAF1, BRAF1, NS7, RAFB1

Location

GRCh37:CM000669.1

About this gene

This gene has 5 transcripts (splice variants), 16 paralogues and is associated with 160 phenotypes.

Transcripts

Transcript ID	Name	bp	Protein	Translation ID	Biotype	CCDS	UniProt Match	RefSeq	Flags
ENST00000288602.6	BRAF-001	2480	766aa	ENSP00000288602.6	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS5863	D7PBN4 E5FF37 P15056 Q75MQ8	NM_004333.4	A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000496384.2	BRAF-003	8294	375aa	ENSP00000419060.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding		E5FF37	-	5' truncation in transcript evidence prevents annotation of the start of the CDS.CDS 5' incomplete,
ENST00000497784.1	BRAF-002	2336	194aa	ENSP00000420119.1	Nonsense mediated decay		H7C5K3	-	5' truncation in transcript evidence prevents annotation of the start of the CDS.CDS 5' incomplete,
ENST00000479537.1	BRAF-005	743	102aa	ENSP00000418033.1	Nonsense mediated decay		E5FF37 H7C4S5	-	5' truncation in transcript evidence prevents annotation of the start of the CDS.CDS 5' incomplete,
ENST00000469930.1	BRAF-004	1058	No protein	-	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron		-	-	-

Summary