Description
epidermal growth factor receptor [Source:HGNC Symbol;Acc:3236]
Gene Synonyms
ERBB, ERBB1, HER1, PIG61, mENA
Location
Chromosome 7: 55,086,714-55,324,313 forward strand.
GRCh37:CM000669.1
About this gene
This gene has 11 transcripts (splice variants), 13 paralogues and is associated with 116 phenotypes.
Transcripts
| Transcript ID | Name | bp | Protein | Translation ID | Biotype | CCDS | UniProt Match | RefSeq | Flags |
|---|---|---|---|---|---|---|---|---|---|
| ENST00000275493.2 | EGFR-001 | 9821 | 1210aa | ENSP00000275493.2 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS5514 | A7VN06 C9JYS6 E9PFD7 F1JTL6 G9MC81 I3WA72 I3WA73 P00533 Q75MF2 | NM_005228.3 | A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, The GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).GENCODE basic, |
| ENST00000454757.2 | EGFR-202 | 3938 | 1157aa | ENSP00000395243.2 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | A7VN06 C9JYS6 E9PFD7 F1JTL6 G9MC81 I3WA72 I3WA73 Q75MF2 | - | The GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).GENCODE basic, | |
| ENST00000455089.1 | EGFR-004 | 3844 | 1091aa | ENSP00000415559.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | A7VN06 F1JTL6 G9MC81 I3WA72 I3WA73 Q504U8 | - | The GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).GENCODE basic, | |
| ENST00000344576.2 | EGFR-002 | 2864 | 705aa | ENSP00000345973.2 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS5515 | C9JYS6 F1JTL6 P00533 Q9H3C8 | NM_201284.1 | The GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).GENCODE basic, |
| ENST00000442591.1 | EGFR-201 | 2529 | 657aa | ENSP00000410031.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | C9JYS6 F1JTL6 Q9H3D0 | - | The GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).GENCODE basic, | |
| ENST00000342916.3 | EGFR-003 | 2239 | 628aa | ENSP00000342376.3 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS5516 | C9JYS6 F1JTL6 P00533 | NM_201282.1 | The GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).GENCODE basic, |
| ENST00000420316.2 | EGFR-005 | 1570 | 405aa | ENSP00000413843.2 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS47587 | C9JYS6 P00533 Q8WZA5 | NM_201283.1 | The GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).GENCODE basic, |
| ENST00000450046.1 | EGFR-009 | 691 | 128aa | ENSP00000413354.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | C9JYS6 | - | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete, | |
| ENST00000463948.1 | EGFR-008 | 561 | No protein | - | Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript | - | - | - | |
| ENST00000459688.1 | EGFR-007 | 452 | No protein | - | Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript | - | - | - | |
| ENST00000485503.1 | EGFR-010 | 665 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | - |
