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Summary
- Splice variants
- Transcript comparison
- Gene alleles
Sequence
- Secondary Structure
Comparative Genomics
- Paralogues
- Genomic alignments
- Gene tree
- Gene gain/loss tree
- Orthologues
Ontologies
Phenotypes
Genetic Variation
Gene expression
Pathway
Molecular interactions
Regulation
External references
Supporting evidence
ID History
- Gene history

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Gene: APOE ENSG00000130203

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Description

apolipoprotein E [Source:HGNC Symbol;Acc:613]

Gene Synonyms

AD2, LDLCQ5, LPG

Location

Chromosome 19: 45,409,011-45,412,650 forward strand.

GRCh37:CM000681.1

About this gene

This gene has 5 transcripts (splice variants) and is associated with 11 phenotypes.

Transcripts

Show transcript tableHide transcript table

Transcript ID	Name	bp	Protein	Translation ID	Biotype	CCDS	UniProt Match	RefSeq	Flags
ENST00000252486.4	APOE-001	1208	317aa	ENSP00000252486.3	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS12647	E7ERP7 E9PEV4 J9ZVQ3 P02649 Q6LA97 Q6LBZ1	NM_000041.2	A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, The GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).GENCODE basic,
ENST00000425718.1	APOE-005	923	219aa	ENSP00000410423.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding		E7ERP7 E9PEV4 Q6LA97	-	3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete,
ENST00000434152.1	APOE-004	864	269aa	ENSP00000413653.2	Gene/transcipt that contains an open reading frame (ORF).Protein coding		E7ERP7 E9PEV4 H0Y7L5 Q6LA97 Q6LBZ1	-	3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete,
ENST00000446996.1	APOE-002	737	216aa	ENSP00000413135.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding		E9PEV4 Q6LA97	-	3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete,
ENST00000485628.2	APOE-003	771	No protein	-	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron		-	-	-

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Summary

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