Gene: GCLC ENSG00000001084

Description

glutamate-cysteine ligase, catalytic subunit [Source:HGNC Symbol;Acc:4311]

Gene Synonyms

GCL, GCS, GLCL, GLCLC

Location

Chromosome 6: 53,362,139-53,481,768 reverse strand.

GRCh37:CM000668.1

About this gene

This gene has 12 transcripts (splice variants) and is associated with 3 phenotypes.

Transcripts

Show transcript tableHide transcript table

Transcript ID	Name	bp	Protein	Translation ID	Biotype	CCDS	UniProt Match	RefSeq	Flags
ENST00000229416.6	GCLC-001	3813	637aa	ENSP00000229416.6	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS4952	B4E2I4 D6R959 P48506 Q14TF0	NM_001498.3	A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, The GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).GENCODE basic,
ENST00000514004.1	GCLC-003	2356	252aa	ENSP00000421908.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding		D6R959 P48506	-	The GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).GENCODE basic,
ENST00000505197.1	GCLC-013	592	18aa	ENSP00000427403.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding		-	-	3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete,
ENST00000514933.1	GCLC-006	542	154aa	ENSP00000423615.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding		D6R959	-	3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete,
ENST00000513939.1	GCLC-009	519	173aa	ENSP00000424211.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding		-	-	5' and 3' truncations in transcript evidence prevent annotation of the start and the end of the CDS.CDS 5' and 3' incomplete,
ENST00000514373.1	GCLC-010	331	94aa	ENSP00000426578.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding		-	-	5' truncation in transcript evidence prevents annotation of the start of the CDS.CDS 5' incomplete,
ENST00000504525.1	GCLC-008	1011	54aa	ENSP00000421228.1	Nonsense mediated decay		D6RGF8	-	-
ENST00000505294.1	GCLC-007	847	122aa	ENSP00000421629.1	Nonsense mediated decay		D6REX4	-	-
ENST00000509541.1	GCLC-005	3774	No protein	-	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron		-	-	-
ENST00000515580.1	GCLC-004	2132	No protein	-	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron		-	-	-
ENST00000510837.1	GCLC-011	776	No protein	-	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron		-	-	-
ENST00000504353.1	GCLC-012	597	No protein	-	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron		-	-	-

EMBL-EBI User Survey 2024

Gene: GCLC ENSG00000001084

Summary

EMBL-EBI User Survey 2024

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Gene: GCLC ENSG00000001084

Summary