Gene: SMPD4 ENSG00000136699

Description

sphingomyelin phosphodiesterase 4, neutral membrane (neutral sphingomyelinase-3) [Source:HGNC Symbol;Acc:32949]

Gene Synonyms

FLJ20297, FLJ20756, KIAA1418, NET13, NSMASE-3, NSMASE3, nSMase-3

Location

Chromosome 2: 130,908,981-130,940,323 reverse strand.

GRCh37:CM000664.1

About this gene

This gene has 25 transcripts (splice variants), 207 orthologues and is associated with 2 phenotypes.

Transcripts

Show transcript tableHide transcript table

Transcript ID	Name	bp	Protein	Translation ID	Biotype	CCDS	UniProt Match	RefSeq	Flags
ENST00000409031.1	SMPD4-001	4896	866aa	ENSP00000386531.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS42751	B1PBA3 C9J647	NM_017951.4	A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000431183.2	SMPD4-203	4590	764aa	ENSP00000405187.2	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS54398	B4DWK7 Q9NXE4	NM_001171083.2	A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000351288.6	SMPD4-002	3661	837aa	ENSP00000259217.8	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS2156	B4DWK7 C9J647 H7BXF4	NM_017751.4	A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000439886.1	SMPD4-004	3371	741aa	ENSP00000401648.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding		-	-	5' truncation in transcript evidence prevents annotation of the start of the CDS.CDS 5' incomplete,
ENST00000453750.1	SMPD4-206	2994	615aa	ENSP00000394313.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding		B4DM23 B4DWK7	-	A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000339679.7	SMPD4-201	2723	724aa	ENSP00000339721.7	Gene/transcipt that contains an open reading frame (ORF).Protein coding		B4DWK7 G8JLC4	-	A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000443958.2	SMPD4-204	2350	530aa	ENSP00000391896.2	Gene/transcipt that contains an open reading frame (ORF).Protein coding		B4DWK7	-	A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000452225.2	SMPD4-205	2342	607aa	ENSP00000387762.2	Gene/transcipt that contains an open reading frame (ORF).Protein coding		B4DQ31	-	A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000426662.2	SMPD4-202	1861	502aa	ENSP00000397479.2	Gene/transcipt that contains an open reading frame (ORF).Protein coding		B4E0L6	-	A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENST00000457039.2	SMPD4-014	940	313aa	ENSP00000397078.2	Gene/transcipt that contains an open reading frame (ORF).Protein coding		H7C0W5	-	5' and 3' truncations in transcript evidence prevent annotation of the start and the end of the CDS.CDS 5' and 3' incomplete,
ENST00000430682.1	SMPD4-015	820	274aa	ENSP00000406325.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding		-	-	5' and 3' truncations in transcript evidence prevent annotation of the start and the end of the CDS.CDS 5' and 3' incomplete,
ENST00000451542.1	SMPD4-016	796	265aa	ENSP00000405363.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding		H7C2E2	-	5' and 3' truncations in transcript evidence prevent annotation of the start and the end of the CDS.CDS 5' and 3' incomplete,
ENST00000441135.1	SMPD4-020	699	135aa	ENSP00000406458.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding		C9J647	-	3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete,
ENST00000449159.1	SMPD4-009	635	211aa	ENSP00000403915.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding		H7C235	-	5' and 3' truncations in transcript evidence prevent annotation of the start and the end of the CDS.CDS 5' and 3' incomplete,
ENST00000412570.1	SMPD4-013	3601	57aa	ENSP00000403002.1	Nonsense mediated decay		F2Z2W5	-	-
ENST00000454468.1	SMPD4-011	3583	50aa	ENSP00000407591.1	Nonsense mediated decay		F8WF03	-	-
ENST00000433118.1	SMPD4-012	3335	56aa	ENSP00000397278.1	Nonsense mediated decay		F2Z2I0	-	-
ENST00000435455.1	SMPD4-010	842	88aa	ENSP00000393791.1	Nonsense mediated decay		F8WEQ5	-	-
ENST00000439029.1	SMPD4-019	566	56aa	ENSP00000416208.1	Nonsense mediated decay		F2Z2I0	-	-
ENST00000473720.1	SMPD4-017	555	No protein	-	Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript		-	-	-
ENST00000455548.2	SMPD4-018	547	No protein	-	Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript		-	-	-
ENST00000482171.1	SMPD4-005	4298	No protein	-	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron		-	-	-
ENST00000491128.1	SMPD4-006	2570	No protein	-	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron		-	-	-
ENST00000461187.1	SMPD4-008	659	No protein	-	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron		-	-	-
ENST00000491319.2	SMPD4-007	593	No protein	-	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron		-	-	-

Gene gain/loss tree

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Gene: SMPD4 ENSG00000136699

Gene gain/loss tree