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Summary
- Splice variants
- Transcript comparison
- Gene alleles
Sequence
- Secondary Structure
Comparative Genomics
- Paralogues
- Genomic alignments
- Gene tree
- Gene gain/loss tree
- Orthologues
Ontologies
- GO: Biological process
- GO: Molecular function
- GO: Cellular component
Phenotypes
Genetic Variation
Gene expression
Pathway
Molecular interactions
Regulation
External references
Supporting evidence
ID History
- Gene history

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Gene: MLKL ENSG00000168404

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Description

mixed lineage kinase domain-like [Source:HGNC Symbol;Acc:26617]

Gene Synonyms

FLJ34389

Location

Chromosome 16: 74,705,753-74,734,858 reverse strand.

GRCh37:CM000678.1

About this gene

This gene has 8 transcripts (splice variants).

Transcripts

Show transcript tableHide transcript table

Transcript ID	Name	bp	Protein	Translation ID	Biotype	CCDS	UniProt Match	RefSeq	Flags
ENST00000308807.7	MLKL-001	2523	471aa	ENSP00000308351.7	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS32487	I3L2T9 I3L4Z5 Q8NB16	NM_152649.2	A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, The GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).GENCODE basic,
ENST00000306247.7	MLKL-002	1781	263aa	ENSP00000303118.7	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS45528	I3L4Z5 Q8NB16	NM_001142497.1	The GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).GENCODE basic,
ENST00000573267.1	MLKL-005	1004	211aa	ENSP00000459920.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding		I3L2T9 I3L4Z5	-	3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete,
ENST00000575686.1	MLKL-006	567	62aa	ENSP00000461666.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding		I3L4Z5	-	3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete,
ENST00000576529.1	MLKL-008	458	102aa	ENSP00000459935.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding		-	-	5' truncation in transcript evidence prevents annotation of the start of the CDS.CDS 5' incomplete,
ENST00000571303.1	MLKL-007	781	175aa	ENSP00000461110.1	Nonsense mediated decay		-	-	5' truncation in transcript evidence prevents annotation of the start of the CDS.CDS 5' incomplete,
ENST00000570846.1	MLKL-003	3882	No protein	-	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron		-	-	-
ENST00000575695.1	MLKL-004	2566	No protein	-	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron		-	-	-

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Summary

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